SCHEMBL21745872

SCHEMBL21745872

CN/C=C(/Br)C(=N)NC(C)=O

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21746989 0.75
SCHEMBL18463801 0.73 SMN1; SMN2 (0.30)
SCHEMBL5028216 0.72
SCHEMBL22457257 0.67
SCHEMBL24006834 0.67
SCHEMBL21746990 0.67
SCHEMBL21746681 0.66
SCHEMBL15998927 0.66
SCHEMBL21746563 0.66
SCHEMBL26011744 0.65 TAS2R38 (0.36) CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2944637-B1 NITROGEN-CONTAINING HETEROCYLIC COMPOUND OR SALT THEREOF FUJIFILM CORP (JP) 2020-02-19 EP disclosed