Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 2/20 | 0.53 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.43 |
| ▸ | WNT1 | P04628 | 4/20 | 0.41 |
| ▸ | GSK3B | P49841 | 4/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.41 |
| ▸ | RAF1 | P04049 | 7/20 | 0.41 |
| ▸ | BRAF | P15056 | 7/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4411361 | 0.75 | PIK3CA (0.63) | PIK3CAMAPK13WNT1GSK3BDYRK1A | |
| SCHEMBL19672209 | 0.74 | PIK3CA (0.45) | PIK3CAMAPK13WNT1GSK3BDYRK1A | |
| SCHEMBL13702422 | 0.74 | PIK3CA (0.70) | PIK3CAMAPK13WNT1GSK3BDYRK1A | |
| SCHEMBL19671935 | 0.73 | PIK3CA (0.43) | PIK3CAMAPK13WNT1GSK3BDYRK1A | |
| SCHEMBL19672208 | 0.73 | PIK3CA (0.43) | PIK3CAMAPK13WNT1GSK3BDYRK1A | |
| SCHEMBL12639899 | 0.72 | PIK3CA (0.76) | PIK3CAMAPK13WNT1GSK3BDYRK1A | |
| SCHEMBL19672122 | 0.71 | PIK3CA (0.42) | PIK3CAMAPK13WNT1GSK3BDYRK1A | |
| SCHEMBL31704530 | 0.71 | PIK3CA (0.74) | PIK3CAMAPK13WNT1GSK3BDYRK1A | |
| SCHEMBL21746607 | 0.71 | PROKR1 (0.33) | WNT1GSK3BDYRK1A | |
| SCHEMBL1516978 | 0.71 | PIK3CA (0.74) | PIK3CAMAPK13WNT1GSK3BDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2944637-B1 | NITROGEN-CONTAINING HETEROCYLIC COMPOUND OR SALT THEREOF | FUJIFILM CORP (JP) | 2020-02-19 | — | — | EP | disclosed |