SCHEMBL21746435

SCHEMBL21746435

FC(F)(F)C1CCN(I)C1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SPR P35270 1/20 0.31
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12070424 1.00 SPR (0.31) SPRPOLB
SCHEMBL12070416 1.00 SPR (0.31) SPRPOLB
SCHEMBL12070423 0.86 POLB (0.38) POLB
SCHEMBL12070417 0.86 POLB (0.38) POLB
SCHEMBL19416101 0.86 POLB (0.38) POLB
SCHEMBL15935898 0.84
SCHEMBL17085411 0.78
SCHEMBL21393200 0.75 CYP2D6 (0.32)
SCHEMBL18654949 0.72 SPR (0.32) SPRPOLB
SCHEMBL21341548 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020035540-A1 HETEROAROMATIC CARBOXAMIDE DERIVATIVES AS PLASMA KALLIKREIN INHIBITORS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2020-02-20 WO disclosed