Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24354654 | 1.00 | APLNR (0.31) | APLNR | |
| SCHEMBL21736607 | 0.72 | APLNR (0.31) | APLNR | |
| SCHEMBL24354653 | 0.72 | APLNR (0.31) | APLNR | |
| SCHEMBL21574872 | 0.71 | — | — | |
| SCHEMBL21427331 | 0.71 | APLNR (0.42) | APLNR | |
| SCHEMBL22098614 | 0.69 | GRIN2B (0.31) | — | |
| SCHEMBL19754771 | 0.69 | GRIN2B (0.31) | — | |
| SCHEMBL23862402 | 0.67 | ATM (0.32) | — | |
| SCHEMBL23277735 | 0.67 | ATM (0.32) | — | |
| SCHEMBL24869671 | 0.67 | APLNR (0.32) | APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020035540-A1 | HETEROAROMATIC CARBOXAMIDE DERIVATIVES AS PLASMA KALLIKREIN INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2020-02-20 | — | — | WO | disclosed |