Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18246071 | 1.00 | APLNR (1.00) | APLNR | |
| SCHEMBL30727133 | 1.00 | APLNR (1.00) | APLNR | |
| SCHEMBL18246793 | 1.00 | APLNR (1.00) | APLNR | |
| SCHEMBL18246561 | 0.94 | APLNR (1.00) | APLNR | |
| SCHEMBL21748121 | 0.94 | APLNR (1.00) | APLNR | |
| SCHEMBL18490873 | 0.94 | APLNR (1.00) | APLNR | |
| SCHEMBL18246051 | 0.94 | APLNR (1.00) | APLNR | |
| SCHEMBL18246374 | 0.94 | APLNR (1.00) | APLNR | |
| SCHEMBL18245657 | 0.93 | APLNR (1.00) | APLNR | |
| SCHEMBL21097434 | 0.93 | APLNR (1.00) | APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3300500-B9 | TRIAZOLE AGONISTS OF THE APJ RECEPTOR | AMGEN INC (US) | 2021-01-13 | — | — | EP | claimed |
| CN-108137545-B | Triazole agonists of the APJ receptor | 美国安进公司 | 2020-09-22 | — | — | CN | claimed |
| EP-3300500-B1 | TRIAZOLE AGONISTS OF THE APJ RECEPTOR | AMGEN INC (US) | 2020-02-26 | — | — | EP | claimed |
| CN-117897157-A | Apelin receptor modulators for the treatment of age-related muscle disorders | 百爱及生物医药公司 | 2024-04-16 | — | — | CN | disclosed |
| CN-108137545-B | Triazole agonists of the APJ receptor | 美国安进公司 | 2020-09-22 | — | — | CN | disclosed |