Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30134667 | 1.00 | APLNR (1.00) | APLNR | |
| SCHEMBL18246522 | 1.00 | APLNR (1.00) | APLNR | |
| SCHEMBL18257262 | 0.95 | APLNR (0.91) | APLNR | |
| SCHEMBL18246462 | 0.93 | APLNR (1.00) | APLNR | |
| SCHEMBL18519126 | 0.92 | APLNR (0.85) | APLNR | |
| SCHEMBL18519159 | 0.92 | APLNR (0.85) | APLNR | |
| SCHEMBL28459733 | 0.91 | APLNR (1.00) | APLNR | |
| SCHEMBL18247248 | 0.91 | APLNR (1.00) | APLNR | |
| SCHEMBL18246554 | 0.91 | APLNR (1.00) | APLNR | |
| SCHEMBL21748033 | 0.91 | APLNR (1.00) | APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3300500-B9 | TRIAZOLE AGONISTS OF THE APJ RECEPTOR | AMGEN INC (US) | 2021-01-13 | — | — | EP | claimed |
| EP-3300500-B1 | TRIAZOLE AGONISTS OF THE APJ RECEPTOR | AMGEN INC (US) | 2020-02-26 | — | — | EP | claimed |
| EP-4532015-A1 | APELIN RECEPTOR MODULATORS FOR TREATMENT OF A DISORDER OR DISEASE ASSOCIATED WITH BBB PERMEABILITY | Bioage Labs, Inc. (US) | 2025-04-09 | — | — | EP | disclosed |
| EP-4319873-A1 | APELIN RECEPTOR MODULATORS FOR TREATING AGE-RELATED MUSCLE CONDITIONS | Bioage Labs, Inc. (US) | 2024-02-14 | — | — | EP | disclosed |
| WO-2023235360-A1 | APELIN RECEPTOR MODULATORS FOR TREATMENT OF A DISORDER OR DISEASE ASSOCIATED WITH BBB PERMEABILITY | BioAge Labs, Inc. (US) | 2023-12-07 | — | — | WO | disclosed |