SCHEMBL2174840

SCHEMBL2174840

O=C(O)c1cccc(C(=O)c2ccc(C(=O)O)c(C(=O)OC(=O)c3cc(C(=O)c4cccc(C(=O)O)c4)ccc3C(=O)O)c2)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.60
CDC25A P30304 1/20 0.53
CDC25B P30305 1/20 0.53
HSD17B10 Q99714 1/20 0.53
POLB P06746 3/20 0.51
TDP1 Q9NUW8 2/20 0.51
L3MBTL1 Q9Y468 2/20 0.51
ATM Q13315 1/20 0.48
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
CA9 Q16790 2/20 0.46
SRD5A2 P31213 3/20 0.44
PTPN1 P18031 1/20 0.42
AKR1C3 P42330 2/20 0.42
CYP2C8 P10632 1/20 0.42
CA12 O43570 1/20 0.42
CA6 P23280 1/20 0.42
LMNA P02545 1/20 0.42
RAB9A P51151 1/20 0.42
MYC P01106 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3474963 0.92 KDM4E (0.57) KDM4ECDC25ACDC25BHSD17B10POLB
Isophthalic Acid SCHEMBL19579513 0.90 KDM4E (0.56) KDM4ECDC25ACDC25BHSD17B10POLB
SCHEMBL1271058 0.90 KDM4E (0.64) KDM4ECDC25ACDC25BHSD17B10POLB
SCHEMBL4842453 0.89 CDC25A (0.59) KDM4ECDC25ACDC25BHSD17B10POLB
SCHEMBL2805605 0.88 POLB (0.61) KDM4ECDC25ACDC25BHSD17B10POLB
Isophthalic Acid SCHEMBL11316284 0.88 KDM4E (0.56) KDM4ECDC25ACDC25BHSD17B10POLB
SCHEMBL168534 0.88 POLB (0.65) KDM4ECDC25ACDC25BHSD17B10POLB
SCHEMBL464994 0.88 KDM4E (0.70) KDM4ECDC25ACDC25BHSD17B10POLB
SCHEMBL8650117 0.87 KDM4E (0.59) KDM4ECDC25ACDC25BHSD17B10POLB
Pyromellitic Acid SCHEMBL9244438 0.86 KDM4E (0.68) KDM4ECDC25ACDC25BHSD17B10POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8449200-B2 Resin composition for sliding member and rolling bearing NTN CORPORATION (JP) 2013-05-28 US disclosed
US-8293847-B2 Film-like adhesive, adhesive sheet, and semiconductor device using same HITACHI CHEMICAL CO., LTD. (JP) 2012-10-23 US disclosed
US-8182155-B2 Lubricating grease and lubricating grease-enclosed roller bearing NTN CORPORATION (JP) 2012-05-22 US disclosed
US-7973122-B2 Polyamideimide compositions having multifunctional core structures GENERAL CABLE TECHNOLOGIES CORPORATION (US) 2011-07-05 US disclosed
US-20100239858-A1 FILM-LIKE ADHESIVE, ADHESIVE SHEET, AND SEMICONDUCTOR DEVICE USING SAME HITACHI CHEMICAL CO., LTD., (JP) 2010-09-23 US disclosed
US-20100142872-A1 RESIN COMPOSITION FOR SLIDING MEMBER AND ROLLING BEARING NTN CORPORATION (JP) 2010-06-10 US disclosed
EP-2157135-A1 RESIN COMPOSITION FOR SLIDE MEMBER AND ROLLER BEARING NTN Corporation (JP) 2010-02-24 EP disclosed
US-20090232432-A1 Lubricating grease and lubricating grease-enclosed roller bearing NTN CORPORATION (JP) 2009-09-17 US disclosed
EP-2053108-A1 FILM ADHESIVE, ADHESIVE SHEET, AND SEMICONDUCTOR DEVICE USING THE SAME Hitachi Chemical Co., Ltd. (JP) 2009-04-29 EP disclosed
EP-1956072-A1 LUBRICATING GREASE AND LUBRICATING-GREASE-FILLED ROLLER BEARING NTN CORPORATION (JP) 2008-08-13 EP disclosed
EP-1014766-A2 Flexible board Sony Chemicals Corporation (JP) 2000-06-28 EP disclosed
US-5306785-A Molding materials GENERAL ELECTRIC COMPANY (US) 1994-04-26 US disclosed
EP-0322778-B1 BICOMPONENT MOISTURE BARRIER POLY(ETHERIMIDE) ESTER FILMS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-09-08 EP disclosed
EP-0554369-A1 POLY(ALKYLENE CYCLOHEXANEDICARBOXYLATE) BINARY BLENDS GENERAL ELECTRIC COMPANY (US) 1993-08-11 EP disclosed
EP-0537014-A2 Dual graft stage and thermally stabilized polyorganisiloxane/polyvinyl-based graft copolymers and thermoplastic compositions containing the same GENERAL ELECTRIC COMPANY (US) 1993-04-14 EP disclosed
WO-1993004124-A1 POLY(ALKYLENE CYCLOHEXANEDICARBOXYLATE) BINARY BLENDS GENERAL ELECTRIC COMPANY (US) 1993-03-04 WO disclosed
EP-0322777-B1 VAPOR PERMEABLE POLY(ETHERIMIDE) ESTER ELASTOMER FILMS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-11-04 EP disclosed
EP-0322777-A1 Vapor permeable poly(etherimide) ester elastomer films E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-07-05 EP disclosed
EP-0322778-A2 Bicomponent moisture barrier poly(etherimide) ester films E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-07-05 EP disclosed
US-4769273-A HAVING DIFFERENTIAL TRANSFER OF WATER VAPOR TO PREVENT BUILD-UP; TEXTILE COVERING; SURGICAL DRAPES; WATERPROOFED CLOTHING E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-09-06 US disclosed