Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.53 |
| ▸ | MAPT | P10636 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.53 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.53 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2175431 | 0.88 | MERTK (0.53) | RAB9AMAPTALDH1A1GAAHTT | |
| SCHEMBL2175149 | 0.84 | ALDH1A1 (0.58) | RAB9AMAPTALDH1A1GAAHTT | |
| SCHEMBL2178048 | 0.81 | MERTK (0.56) | RAB9AMAPTALDH1A1GAAHTT | |
| SCHEMBL2175734 | 0.79 | MAPT (0.59) | RAB9AMAPTALDH1A1GAAHTT | |
| SCHEMBL301341 | 0.78 | MAPT (0.76) | RAB9AMAPTALDH1A1GAAHTT | |
| SCHEMBL14518469 | 0.77 | SCN5A (0.66) | RAB9AMAPTKCNH2CACNA1CSCN5A | |
| SCHEMBL12486513 | 0.77 | MEN1 (0.79) | RAB9AMAPTALDH1A1GAAHTT | |
| SCHEMBL793912 | 0.73 | GAA (0.71) | RAB9AMAPTALDH1A1GAAMEN1 | |
| SCHEMBL23221522 | 0.73 | ALDH1A1 (0.50) | RAB9AMAPTALDH1A1GAAMEN1 | |
| SCHEMBL8348068 | 0.73 | GRM5 (0.50) | KCNH2CACNA1CSCN5ATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2519501-A2 | SUBSTITUTED PYRIDINES AND PYRIMIDINES FOR THE PRODUCTION OF CARDIOMYOCYTE-LIKE CELLS | Technische Universität Wien (AT) | 2012-11-07 | — | — | EP | disclosed |
| WO-2011079343-A2 | SUBSTITUTED PYRIDINES AND PYRIMIDINES | TECHNISCHE UNIVERSITAET WIEN (AT) | 2011-07-07 | — | — | WO | disclosed |