⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20494566 | 1.00 | — | — | |
| SCHEMBL10063860 | 1.00 | — | — | |
| SCHEMBL13336655 | 1.00 | — | — | |
| SCHEMBL5775209 | 1.00 | — | — | |
| SCHEMBL12284195 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL1669384 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL20168285 | 0.97 | — | — | |
| SCHEMBL332930 | 0.97 | SLC6A12 (0.38) | — | |
| Hydrochloric Acid SCHEMBL20168701 | 0.97 | — | — | |
| SCHEMBL11046395 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11001586-B2 | Alkyl pyrrolopyrimidine analogs and methods of making and using same | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2021-05-11 | — | — | US | disclosed |
| US-20200062764-A1 | ALKYL PYRROLOPYRIMIDINE ANALOGS AND METHODS OF MAKING AND USING SAME | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2020-02-27 | — | — | US | disclosed |