⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26131903 | 0.86 | BLM (0.38) | — | |
| SCHEMBL5836653 | 0.85 | ALOX15 (0.47) | — | |
| SCHEMBL11679430 | 0.84 | RARB (0.40) | — | |
| SCHEMBL2787526 | 0.83 | BLM (0.50) | — | |
| SCHEMBL8557263 | 0.82 | RARB (0.39) | — | |
| SCHEMBL8559662 | 0.82 | RARB (0.39) | — | |
| SCHEMBL28518589 | 0.82 | RARB (0.39) | — | |
| SCHEMBL28282898 | 0.82 | RARB (0.39) | — | |
| SCHEMBL29116299 | 0.81 | CA1 (0.43) | — | |
| SCHEMBL29059577 | 0.81 | CA1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119504882-A | Synthesis method of GalNAc derivative | 北京炫景瑞医药科技有限公司 | 2025-02-25 | — | — | CN | claimed |
| CN-117164775-A | Composition for preparing gel, preparation method of gel and synergistic improvement of CO 2 Method for recovering crude oil and geological storage rate | 中国石油大学(北京) | 2023-12-05 | — | — | CN | claimed |
| CN-122055369-A | Bridged tricyclic carbamoyl pyridone compounds and uses thereof | 吉利德科学公司 | 2026-05-15 | — | — | CN | disclosed |
| US-12599666-B2 | Photolytic compounds and triplet-triplet annihilation mediated photolysis | UNIVERSITY OF MASSACHUSETTS (US) | 2026-04-14 | — | — | US | disclosed |
| US-20250122219-A1 | BRIDGED TRICYCLIC CARBAMOYLPYRIDONE COMPOUNDS AND USES THEREOF | GILEAD SCIENCES, INC. | 2025-04-17 | — | — | US | disclosed |
| WO-2025080863-A1 | BRIDGED TRICYCLIC CARBAMOYLPYRIDONE COMPOUNDS AND USES THEREOF | GILEAD SCIENCES, INC. (US) | 2025-04-17 | — | — | WO | disclosed |
| EP-4486747-A1 | ANTIVIRAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | GILEAD SCIENCES, INC. (US) | 2025-01-08 | — | — | EP | disclosed |
| CN-118900839-A | Antiviral compounds and methods of making and using the same | 吉利德科学公司 | 2024-11-05 | — | — | CN | disclosed |
| WO-2024094637-A1 | PROCESS FOR THE PREPARATION OF CYCLIC KETONES | ARXADA AG (CH) | 2024-05-10 | — | — | WO | disclosed |
| CN-117903036-A | Synthesis and application of novel FXR (FXR) agonist | 厦门市博瑞来医药科技有限公司 | 2024-04-19 | — | — | CN | disclosed |
| US-20230416275-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED | 2023-12-28 | — | — | US | disclosed |
| US-4409140-A | Substrates and method for determining enzymes | SMITH ROBERT E (US) | 1983-10-11 | — | — | US | disclosed |
| EP-0034586-B1 | 4-TRIFLUOROMETHYLCOUMARIN PEPTIDE DERIVATIVES AND THEIR USE IN PROTEINASE ASSAYS | Smith, Robert Eugene (US) | 1983-08-31 | — | — | EP | disclosed |
| EP-0018112-B1 | SUBSTRATES AND METHOD FOR DETERMINING PROTEOLYTIC ENZYMES | Smith, Robert Eugene (US) | 1983-07-20 | — | — | EP | disclosed |
| US-4294923-A | AMINO ACID DERIVATIVE OF 7-AMINO-4-TRIFLUOROMETHYL COUMARIN HYDROLYZED TO FREE CHROMOPHORE | SMITH ROBERT E | 1981-10-13 | — | — | US | disclosed |
| EP-0034586-A1 | 4-TRIFLUOROMETHYLCOUMARIN PEPTIDE DERIVATIVES AND THEIR USE IN PROTEINASE ASSAYS. | SMITH ROBERT EUGENE (US) | 1981-09-02 | — | — | EP | disclosed |
| EP-0034586-A4 | 4-TRIFLUOROMETHYLCOUMARIN PEPTIDE DERIVATIVES AND THEIR USE IN PROTEINASE ASSAYS. | SMITH ROBERT EUGENE (US) | 1981-05-15 | — | — | EP | disclosed |
| WO-1980002295-A1 | 4-TRIFLUOROMETHYLCOUMARIN PEPTIDE DERIVATIVES AND THEIR USE IN PROTEINASE ASSAYS | SMITH R (US) | 1980-10-30 | — | — | WO | disclosed |
| EP-0018112-A1 | Substrates and method for determining proteolytic enzymes | Smith, Robert Eugene (US) | 1980-10-29 | — | — | EP | disclosed |
| US-3975538-A | O-ALKOXYCARBONYL-2-ALKOXY-1-NAPHTHOHYDROXAMATES | TAKEDA CHEMICAL INDUSTRIES, INC. (JA) | 1976-08-17 | — | — | US | disclosed |