Thiourea

Thiourea

SCHEMBL21751250

Fc1cccc(OC(F)F)c1CBr.N=C(N)S

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 2/20 0.39
SLC6A4 P31645 2/20 0.39
KCNH2 Q12809 2/20 0.39
KMT2A Q03164 1/20 0.37
POLB P06746 1/20 0.36
BACE1 P56817 1/20 0.35
ALDH1A1 P00352 1/20 0.33
HTT P42858 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18149715 0.88 SLC6A2 (0.46) SLC6A2SLC6A4KCNH2KMT2APOLB
SCHEMBL21763692 0.77 BACE1 (0.58) SLC6A2SLC6A4KCNH2KMT2ABACE1
Bromide SCHEMBL21751249 0.76 BACE1 (0.57) SLC6A2SLC6A4KCNH2BACE1ALDH1A1
SCHEMBL16797182 0.75 SLC6A2 (0.46) SLC6A2SLC6A4KCNH2KMT2APOLB
SCHEMBL18150337 0.75 SLC6A2 (0.46) SLC6A2SLC6A4KCNH2KMT2APOLB
SCHEMBL30540309 0.75 KMT2A (0.46) SLC6A2SLC6A4KCNH2KMT2APOLB
SCHEMBL28562728 0.73 MCHR1 (0.36) SLC6A2SLC6A4KCNH2KMT2APOLB
SCHEMBL900189 0.72 SLC6A2 (0.46) SLC6A2SLC6A4KCNH2KMT2APOLB
SCHEMBL16797141 0.72 KMT2A (0.39) SLC6A2SLC6A4KCNH2KMT2APOLB
SCHEMBL25767325 0.72 SLC6A2 (0.46) SLC6A2SLC6A4KCNH2KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200060276-A1 THIAZOLE COMPOUND AND HERBICIDE OAT AGRIO CO., LTD. (JP) 2020-02-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200060276-A1 THIAZOLE COMPOUND AND HERBICIDE OR10J3, OXSR1, OXER1 SLC6A2 3745/4885SLC6A4 1895/4885KCNH2 1779/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.