Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.32 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20541242 | 1.00 | LMNA (0.44) | LMNATSHRALDH1A1USP2KDM4E | |
| SCHEMBL20139585 | 1.00 | LMNA (0.44) | LMNATSHRALDH1A1USP2KDM4E | |
| SCHEMBL21751837 | 1.00 | LMNA (0.44) | LMNATSHRALDH1A1USP2KDM4E | |
| SCHEMBL28513153 | 0.88 | TSHR (0.46) | LMNATSHRALDH1A1USP2KDM4E | |
| SCHEMBL22367403 | 0.88 | TSHR (0.46) | LMNATSHRALDH1A1USP2KDM4E | |
| SCHEMBL2069595 | 0.87 | LMNA (0.52) | LMNATSHRALDH1A1USP2KDM4E | |
| SCHEMBL18530451 | 0.83 | TSHR (0.44) | LMNATSHRALDH1A1USP2KDM4E | |
| SCHEMBL21070639 | 0.83 | TSHR (0.44) | LMNATSHRALDH1A1USP2KDM4E | |
| SCHEMBL21070916 | 0.83 | TSHR (0.44) | LMNATSHRALDH1A1USP2KDM4E | |
| SCHEMBL19434532 | 0.83 | TSHR (0.44) | LMNATSHRALDH1A1USP2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020041406-A1 | BCL-2 INHIBITORS | NEWAVE PHARMACEUTICAL INC. (US) | 2020-02-27 | — | — | WO | disclosed |