Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
| ▸ | APAF1 | O14727 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25886857 | 0.97 | DGAT1 (0.38) | DGAT1HRH3 | |
| SCHEMBL21751562 | 0.93 | DGAT1 (0.38) | DGAT1 | |
| Ammonia Solution, Strong SCHEMBL28939497 | 0.92 | DGAT1 (0.38) | DGAT1 | |
| SCHEMBL21751788 | 0.89 | DGAT1 (0.36) | DGAT1 | |
| SCHEMBL23165244 | 0.89 | DGAT1 (0.37) | DGAT1 | |
| SCHEMBL30018625 | 0.89 | DGAT1 (0.37) | DGAT1 | |
| SCHEMBL25615934 | 0.89 | DGAT1 (0.37) | DGAT1 | |
| SCHEMBL25349464 | 0.85 | DGAT1 (0.38) | DGAT1 | |
| SCHEMBL20767577 | 0.84 | DGAT1 (0.34) | DGAT1 | |
| SCHEMBL26195129 | 0.83 | DGAT1 (0.34) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020041406-A1 | BCL-2 INHIBITORS | NEWAVE PHARMACEUTICAL INC. (US) | 2020-02-27 | — | — | WO | disclosed |