SCHEMBL21753579

SCHEMBL21753579

N[C@@H](CCC(=O)OC(=O)[C@@H](N)CC(=O)O)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A1 P43005 2/20 0.53
GRM8 O00222 2/20 0.53
GRM6 O15303 2/20 0.53
GRM7 Q14831 2/20 0.53
GRM4 Q14833 2/20 0.53
GSR P00390 2/20 0.53
GRIN2D O15399 1/20 0.53
GRIN3B O60391 1/20 0.53
CYP1A2 P05177 1/20 0.53
GRIK1 P39086 1/20 0.53
GRM5 P41594 1/20 0.53
GRIA1 P42261 1/20 0.53
GRIA2 P42262 1/20 0.53
GRIA3 P42263 1/20 0.53
SLC1A3 P43003 1/20 0.53
SLC1A2 P43004 1/20 0.53
GRIA4 P48058 1/20 0.53
GRIN1 Q05586 1/20 0.53
GRIN2A Q12879 1/20 0.53
GRIK2 Q13002 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1276948 0.91 SLC1A1 (0.41) SLC1A1GRM8GRM6GRM7GRM4
SCHEMBL1410127 0.89 SLC1A1 (0.48) SLC1A1GRM8GRM6GRM7GRM4
SCHEMBL7614969 0.88 KMT2A (0.55) SLC1A1GRM8GRM6GRM7GRM4
SCHEMBL31206935 0.87 GRM8 (0.67) SLC1A1GRM8GRM6GRM7GRM4
SCHEMBL20508769 0.87 GRM8 (0.67) SLC1A1GRM8GRM6GRM7GRM4
SCHEMBL3430330 0.87 SLC1A1 (0.54) SLC1A1GRM8GRM6GRM7GRM4
SCHEMBL6267781 0.87 SLC1A1 (0.54) SLC1A1GRM8GRM6GRM7GRM4
SCHEMBL7717181 0.87 SLC1A1 (0.54) SLC1A1GRM8GRM6GRM7GRM4
SCHEMBL3918242 0.87 SLC1A1 (0.54) SLC1A1GRM8GRM6GRM7GRM4
SCHEMBL2994699 0.87 SLC1A1 (0.54) SLC1A1GRM8GRM6GRM7GRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020038464-A1 FIBRIC ACID COMPOUND AND MEDICAL USE THEREOF 北京厚燊药德科技有限责任公司 2020-02-27 WO disclosed