SCHEMBL7614969

SCHEMBL7614969

NC(=O)C[C@H](N)C(=O)OC(=O)CC[C@H](N)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.55
ALOX15 P16050 1/20 0.55
BLM P54132 1/20 0.55
PMP22 Q01453 1/20 0.55
SLC1A1 P43005 2/20 0.47
GSR P00390 2/20 0.47
CYP1A2 P05177 2/20 0.47
GRIK1 P39086 2/20 0.47
GRIK2 Q13002 2/20 0.47
GRM8 O00222 2/20 0.47
GRM6 O15303 2/20 0.47
GRM7 Q14831 2/20 0.47
GRM4 Q14833 2/20 0.47
GRIN2D O15399 1/20 0.47
GRIN3B O60391 1/20 0.47
GRM5 P41594 1/20 0.47
GRIA1 P42261 1/20 0.47
GRIA2 P42262 1/20 0.47
GRIA3 P42263 1/20 0.47
SLC1A3 P43003 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5187828 0.89 ALOX15 (0.39) KMT2AALOX15BLMPMP22SLC1A1
SCHEMBL16054489 0.89 ALOX15 (0.43) KMT2AALOX15BLMPMP22SLC1A1
SCHEMBL21753579 0.88 SLC1A1 (0.53) KMT2AALOX15BLMPMP22SLC1A1
SCHEMBL2443865 0.88 KMT2A (0.68) KMT2AALOX15BLMPMP22SLC1A1
SCHEMBL1410127 0.88 SLC1A1 (0.48) KMT2AALOX15BLMPMP22SLC1A1
SCHEMBL7717181 0.85 SLC1A1 (0.54) KMT2AALOX15BLMPMP22SLC1A1
SCHEMBL3430330 0.85 SLC1A1 (0.54) KMT2AALOX15BLMPMP22SLC1A1
SCHEMBL6267781 0.85 SLC1A1 (0.54) KMT2AALOX15BLMPMP22SLC1A1
SCHEMBL3918242 0.85 SLC1A1 (0.54) KMT2AALOX15BLMPMP22SLC1A1
SCHEMBL931954 0.85 SLC1A1 (0.54) KMT2AALOX15BLMPMP22SLC1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11760775-B2 Steroids and protein-conjugates thereof REGENERON PHARMACEUTICALS, INC. 2023-09-19 US disclosed
US-20210040144-A1 STEROIDS AND PROTEIN-CONJUGATES THEREOF REGENERON PHARMACEUTICALS, INC. 2021-02-11 US disclosed
EP-3737420-A2 STEROIDS AND ANTIBODY-CONJUGATES THEREOF Regeneron Pharmaceuticals, Inc. (US) 2020-11-18 EP disclosed
WO-2019136487-A2 STEROIDS AND ANTIBODY-CONJUGATES THEREOF REGENERON PHARMACEUTICALS, INC. (US) 2019-07-11 WO disclosed
US-20180291077-A1 METHOD OF INSULIN PRODUCTION HANMI PHARM. CO., LTD (KR) 2018-10-11 US disclosed
EP-3341405-A1 METHOD OF INSULIN PRODUCTION Hanmi Pharm. Co., Ltd. (KR) 2018-07-04 EP disclosed
WO-2017052305-A1 METHOD OF INSULIN PRODUCTION HANMI PHARM. CO., LTD. (KR) 2017-03-30 WO disclosed
US-20020151482-A1 Plasminogen-related gene B Polypeptides NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR 2002-10-17 US disclosed
WO-1999058640-A2 MCT-1, A HUMAN ONCOGENE PHILADELPHIA HEALTH AND EDUCATION CORPORATION (US) 1999-11-18 WO disclosed
EP-0391629-B1 Inhibition of mineral deposition by phosphorylated and related polyanionic peptides UNIV SOUTH ALABAMA (US) 1997-05-21 EP disclosed
US-5051401-A A phospho aminoacid polymer as an antideposit agent UNIVERSITY OF SOUTH ALABAMA (US) 1991-09-24 US disclosed
EP-0391629-A1 Inhibition of mineral deposition by phosphorylated and related polyanionic peptides UNIVERSITY OF SOUTH ALABAMA (US) 1990-10-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210040144-A1 STEROIDS AND PROTEIN-CONJUGATES THEREOF SERPINA6, NR3C1, NR3C2 KMT2A 4548/4885ALOX15 2615/4885BLM 3502/4885
US-11760775-B2 Steroids and protein-conjugates thereof SERPINA6, NR3C1, NR3C2 KMT2A 4548/4885ALOX15 2615/4885BLM 3502/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.