Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS2 | Q8NHU3 | 3/20 | 0.64 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.62 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | PARP1 | P09874 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL29914194 | 1.00 | SGMS2 (0.64) | SGMS2FOLH1PTGER1ALDH1A1KMT2A | |
| Bicarbonate SCHEMBL236872 | 1.00 | SGMS2 (0.64) | SGMS2FOLH1PTGER1ALDH1A1KMT2A | |
| SCHEMBL29433417 | 0.98 | SGMS2 (0.66) | SGMS2FOLH1PTGER1ALDH1A1KMT2A | |
| SCHEMBL112903 | 0.98 | SGMS2 (0.66) | SGMS2FOLH1PTGER1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL8998291 | 0.96 | SGMS2 (0.64) | SGMS2FOLH1PTGER1ALDH1A1KMT2A | |
| SCHEMBL17799483 | 0.96 | SGMS2 (0.64) | SGMS2FOLH1PTGER1ALDH1A1KMT2A | |
| Ethyne SCHEMBL29820055 | 0.95 | SGMS2 (0.62) | SGMS2FOLH1PTGER1ALDH1A1KMT2A | |
| SCHEMBL5839516 | 0.90 | NR4A1 (0.63) | SGMS2FOLH1PTGER1ALDH1A1PARP1 | |
| SCHEMBL27610143 | 0.89 | GAA (0.64) | SGMS2FOLH1PTGER1ALDH1A1KMT2A | |
| SCHEMBL8786705 | 0.89 | SGMS2 (0.64) | SGMS2FOLH1PTGER1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114650915-B | Layer structure with modified structure and production thereof | 科思创德国股份有限公司 | 2024-05-31 | — | — | CN | disclosed |
| CN-117203063-A | Method for locally coloring plastic parts using solid dyes in a color carrier layer | 科思创德国股份有限公司 | 2023-12-08 | — | — | CN | disclosed |
| EP-4073151-A1 | FILMS HAVING SPECIAL PROPERTIES | Covestro Intellectual Property GmbH & Co. KG (DE) | 2022-10-19 | — | — | EP | disclosed |
| EP-4061644-A1 | LAYER STRUCTURE WITH MODIFIED STRUCTURE, AND PRODUCTION THEREOF | Covestro Intellectual Property GmbH & Co. KG (DE) | 2022-09-28 | — | — | EP | disclosed |
| EP-3880474-A1 | PLASTIC FILMS HAVING HIGH OPACITY AND LOW TRANSPARENCY FOR ID DOCUMENTS HAVING A TRANSPARENT WINDOW | Covestro Intellectual Property GmbH & Co. KG (DE) | 2021-09-22 | — | — | EP | disclosed |
| EP-3849794-A1 | METHOD FOR MANUFACTURING A LAMINATE WHICH COMPRISES ELECTRONIC COMPONENTS AND/OR FUNTIONAL UNITS | Covestro Intellectual Property GmbH & Co. KG (DE) | 2021-07-21 | — | — | EP | disclosed |
| EP-3840958-A1 | IMPROVED METHOD FOR THE PARTIAL COLORING OF PLASTIC PARTS | Covestro Intellectual Property GmbH & Co. KG (DE) | 2021-06-30 | — | — | EP | disclosed |
| WO-2021116356-A1 | FILMS HAVING SPECIAL PROPERTIES | COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) | 2021-06-17 | — | — | WO | disclosed |
| EP-3721292-A1 | ADHESIVE-FREE PHOTOPOLYMER LAYER STRUCTURE | Covestro Deutschland AG (DE) | 2020-10-14 | — | — | EP | disclosed |
| EP-3645297-A1 | IMPROVED METHOD FOR THE PARTIAL COLOURING OF PLASTIC PARTS | Covestro Deutschland AG (DE) | 2020-05-06 | — | — | EP | disclosed |
| WO-2020053169-A1 | METHOD FOR MANUFACTURING A LAMINATE WHICH COMPRISES ELECTRONIC COMPONENTS AND/OR FUNTIONAL UNITS | COVESTRO DEUTSCHLAND AG (DE) | 2020-03-19 | — | — | WO | disclosed |
| EP-3623148-A1 | METHOD FOR THE PRODUCTION OF A LAMINATE COMPRISING ELECTRONIC COMPONENTS AND/OR FUNCTIONAL UNITS | Covestro Deutschland AG (DE) | 2020-03-18 | — | — | EP | disclosed |
| WO-2020039018-A1 | IMPROVED METHOD FOR THE PARTIAL COLORING OF PLASTIC PARTS | COVESTRO DEUTSCHLAND AG (DE) | 2020-02-27 | — | — | WO | disclosed |
| CN-105829396-B | Preparation of siloxane-containing block copolycarbonates by reactive extrusion | 科思创德国股份有限公司 | 2019-12-20 | — | — | CN | disclosed |