Bicarbonate

Bicarbonate

SCHEMBL21753663

CCCOc1ccccc1C(=O)O.O=C(O)O

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

GSK3AGSK3BIMPA1

The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.69
KMT2A Q03164 4/20 0.69
PTK2B Q14289 1/20 0.69
KDM4E B2RXH2 6/20 0.57
MEN1 O00255 3/20 0.57
HTT P42858 2/20 0.57
HIF1A Q16665 1/20 0.57
LMNA P02545 3/20 0.55
RECQL P46063 1/20 0.55
NR1I2 O75469 1/20 0.55
CHRM2 P08172 1/20 0.55
CYP3A4 P08684 1/20 0.55
ADRA2A P08913 1/20 0.55
MAPT P10636 1/20 0.55
OPRK1 P41145 1/20 0.55
HTR2B P41595 1/20 0.55
SLC6A3 Q01959 1/20 0.55
HDAC6 Q9UBN7 1/20 0.55
HPGD P15428 2/20 0.53
HSD17B10 Q99714 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL29943695 1.00 ALDH1A1 (0.69) ALDH1A1KMT2APTK2BKDM4EMEN1
Bicarbonate SCHEMBL236595 1.00 ALDH1A1 (0.69) ALDH1A1KMT2APTK2BKDM4EMEN1
SCHEMBL31643582 0.98 ALDH1A1 (0.71) ALDH1A1KMT2APTK2BKDM4EMEN1
SCHEMBL124950 0.98 ALDH1A1 (0.71) ALDH1A1KMT2APTK2BKDM4EMEN1
SCHEMBL28219872 0.96 ALDH1A1 (0.69) ALDH1A1KMT2APTK2BKDM4EMEN1
Bicarbonate SCHEMBL29943962 0.91 KMT2A (0.67) ALDH1A1KMT2APTK2BKDM4EMEN1
Benzene SCHEMBL28075108 0.91 KMT2A (0.67) ALDH1A1KMT2APTK2BKDM4EMEN1
Bicarbonate SCHEMBL20694840 0.91 KMT2A (0.67) ALDH1A1KMT2APTK2BKDM4EMEN1
Bicarbonate SCHEMBL237562 0.91 KMT2A (0.67) ALDH1A1KMT2APTK2BKDM4EMEN1
Fumaric Acid SCHEMBL28890188 0.90 ALDH1A1 (0.61) ALDH1A1KMT2APTK2BKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112654508-B Improved method for locally coloring plastic parts 科思创知识产权两合公司 2022-11-08 CN disclosed
EP-4073151-A1 FILMS HAVING SPECIAL PROPERTIES Covestro Intellectual Property GmbH & Co. KG (DE) 2022-10-19 EP disclosed
EP-4061644-A1 LAYER STRUCTURE WITH MODIFIED STRUCTURE, AND PRODUCTION THEREOF Covestro Intellectual Property GmbH & Co. KG (DE) 2022-09-28 EP disclosed
EP-3880474-A1 PLASTIC FILMS HAVING HIGH OPACITY AND LOW TRANSPARENCY FOR ID DOCUMENTS HAVING A TRANSPARENT WINDOW Covestro Intellectual Property GmbH & Co. KG (DE) 2021-09-22 EP disclosed
EP-3849794-A1 METHOD FOR MANUFACTURING A LAMINATE WHICH COMPRISES ELECTRONIC COMPONENTS AND/OR FUNTIONAL UNITS Covestro Intellectual Property GmbH & Co. KG (DE) 2021-07-21 EP disclosed
EP-3840958-A1 IMPROVED METHOD FOR THE PARTIAL COLORING OF PLASTIC PARTS Covestro Intellectual Property GmbH & Co. KG (DE) 2021-06-30 EP disclosed
WO-2021116356-A1 FILMS HAVING SPECIAL PROPERTIES COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2021-06-17 WO disclosed
EP-3727851-A1 PLASTIC FILMS FOR ID DOCUMENTS WITH BETTER LIGHTNESS OF EMBOSSED HOLOGRAMS Covestro Deutschland AG (DE) 2020-10-28 EP disclosed
EP-3721292-A1 ADHESIVE-FREE PHOTOPOLYMER LAYER STRUCTURE Covestro Deutschland AG (DE) 2020-10-14 EP disclosed
WO-2020053169-A1 METHOD FOR MANUFACTURING A LAMINATE WHICH COMPRISES ELECTRONIC COMPONENTS AND/OR FUNTIONAL UNITS COVESTRO DEUTSCHLAND AG (DE) 2020-03-19 WO disclosed
EP-3623148-A1 METHOD FOR THE PRODUCTION OF A LAMINATE COMPRISING ELECTRONIC COMPONENTS AND/OR FUNCTIONAL UNITS Covestro Deutschland AG (DE) 2020-03-18 EP disclosed
WO-2020039018-A1 IMPROVED METHOD FOR THE PARTIAL COLORING OF PLASTIC PARTS COVESTRO DEUTSCHLAND AG (DE) 2020-02-27 WO disclosed