Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.35 |
| ▸ | GAPDH | P04406 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.35 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.35 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.35 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL57983 | 0.95 | TSHR (0.48) | TSHRHPGDTHRBGPR84FFAR1 | |
| SCHEMBL4153752 | 0.93 | TSHR (0.47) | TSHRHPGDTHRBGPR84FFAR1 | |
| SCHEMBL11141006 | 0.93 | TSHR (0.47) | TSHRHPGDTHRBGPR84FFAR1 | |
| SCHEMBL342352 | 0.93 | TSHR (0.47) | TSHRHPGDTHRBGPR84FFAR1 | |
| SCHEMBL7717219 | 0.93 | TSHR (0.47) | TSHRHPGDTHRBGPR84FFAR1 | |
| SCHEMBL11138630 | 0.93 | TSHR (0.47) | TSHRHPGDTHRBGPR84FFAR1 | |
| SCHEMBL8928042 | 0.93 | TSHR (0.47) | TSHRHPGDTHRBGPR84FFAR1 | |
| SCHEMBL11869423 | 0.93 | TSHR (0.47) | TSHRHPGDTHRBGPR84FFAR1 | |
| SCHEMBL1204505 | 0.93 | TSHR (0.47) | TSHRHPGDTHRBGPR84FFAR1 | |
| SCHEMBL342754 | 0.93 | TSHR (0.47) | TSHRHPGDTHRBGPR84FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3840962-A1 | TYRE HAVING A COMPOSITION COMPRISING AN ETHYLENE-RICH ELASTOMER, A PEROXIDE AND A SPECIFIC ACRYLATE DERIVATIVE | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2021-06-30 | — | — | EP | disclosed |
| WO-2020038762-A1 | TYRE HAVING A COMPOSITION COMPRISING AN ETHYLENE-RICH ELASTOMER, A PEROXIDE AND A SPECIFIC ACRYLATE DERIVATIVE | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2020-02-27 | — | — | WO | disclosed |