Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 8/20 | 0.34 |
| ▸ | RXRB | P28702 | 8/20 | 0.34 |
| ▸ | RXRG | P48443 | 8/20 | 0.34 |
| ▸ | KDM5C | P41229 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.30 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21752958 | 0.84 | PDCD1 (0.36) | PDCD1CD274 | |
| SCHEMBL31173435 | 0.82 | PDCD1 (0.40) | PDCD1CD274 | |
| SCHEMBL31173413 | 0.81 | PDCD1 (0.34) | PDCD1CD274 | |
| SCHEMBL30793254 | 0.80 | CHRNB2 (0.32) | PDCD1CD274 | |
| SCHEMBL3548738 | 0.79 | PDCD1 (0.44) | PDCD1CD274 | |
| SCHEMBL31739620 | 0.77 | CXCR4 (0.34) | PDCD1CD274 | |
| SCHEMBL13455832 | 0.75 | PDCD1 (0.44) | PDCD1CD274ITGB3ITGA2B | |
| SCHEMBL16682646 | 0.72 | PDCD1 (0.48) | PDCD1CD274ITGA2B | |
| SCHEMBL30793145 | 0.72 | CXCR4 (0.33) | PDCD1CD274 | |
| SCHEMBL22104649 | 0.72 | PDCD1 (0.41) | PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020040326-A1 | PHENYLACETIC ACID DERIVATIVE, AND COMPOSITION FOR PREVENTING OR TREATING AUTOIMMUNE DISEASES, CONTAINING SAME AS ACTIVE INGREDIENT | 가천대학교 산학협력단 | 2020-02-27 | — | — | WO | disclosed |