Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 2/20 | 0.37 |
| ▸ | GABRD | O14764 | 2/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.37 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.37 |
| ▸ | GABRE | P78334 | 2/20 | 0.37 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.37 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.37 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.37 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3886965 | 0.83 | — | — | |
| SCHEMBL29240935 | 0.81 | OPRM1 (0.34) | OPRM1ALDH1A1 | |
| SCHEMBL3655016 | 0.81 | OPRM1 (0.48) | OPRM1ALDH1A1TDP1TP53GABRP | |
| SCHEMBL4692345 | 0.81 | CYP3A4 (0.42) | ALDH1A1GRM4 | |
| Hydrochloric Acid SCHEMBL5463903 | 0.81 | OPRM1 (0.36) | OPRM1ALDH1A1TDP1GABRPGABRD | |
| SCHEMBL28732357 | 0.80 | OPRM1 (0.42) | OPRM1ALDH1A1TDP1TP53GABRP | |
| SCHEMBL11381711 | 0.80 | TRPV1 (0.36) | GRM4TRPV1TRPA1 | |
| Heptaminol SCHEMBL7530730 | 0.79 | OPRM1 (0.46) | OPRM1ALDH1A1TDP1TP53GABRP | |
| Heptaminol SCHEMBL3163491 | 0.79 | OPRM1 (0.46) | OPRM1ALDH1A1TDP1TP53GABRP | |
| Heptaminol SCHEMBL152610 | 0.79 | OPRM1 (0.46) | OPRM1ALDH1A1TDP1TP53GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118344372-A | Substituted straight-chain spiro derivatives | 詹森药业有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-118255774-A | Substituted straight-chain spiro derivatives | 詹森药业有限公司 | 2024-06-28 | — | — | CN | disclosed |
| CN-118255773-A | Substituted straight-chain spiro derivatives | 詹森药业有限公司 | 2024-06-28 | — | — | CN | disclosed |
| CN-117597348-A | (R) -N-ethyl-5-fluoro-N-isopropyl-2- ((5- (2- (6- ((2-methoxyethyl) (methyl) amino) -2-methylhex-3-yl) -2, 6-diazaspiro [3.4] oct-6-yl) -1,2, 4-triazin-6-yl) oxy) benzamide benzenesulfonate for the treatment of diseases such as cancer | 詹森药业有限公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-117460513-A | Combination therapy | 詹森药业有限公司 | 2024-01-26 | — | — | CN | disclosed |
| CN-117337180-A | combination therapy | 詹森药业有限公司 | 2024-01-02 | — | — | CN | disclosed |
| CN-110770271-B | Method for preparing functionalized fluorinated monomers, fluorinated monomers and compositions for preparing same | 埃特纳科技有限公司 | 2023-04-18 | — | — | CN | disclosed |
| CN-114867721-A | Substituted straight-chain spiro derivatives | 詹森药业有限公司 | 2022-08-05 | — | — | CN | disclosed |
| WO-2020040283-A1 | POLYAMIDE COMPOSITION | 株式会社クラレ | 2020-02-27 | — | — | WO | disclosed |
| WO-2020040282-A1 | POLYAMIDE AND POLYAMIDE COMPOSITION | 株式会社クラレ | 2020-02-27 | — | — | WO | disclosed |
| CN-101180322-A | Process for producing aqueous polymer dispersions | BASF AG (DE) | 2008-05-14 | — | — | CN | disclosed |