Phosphine

Phosphine

SCHEMBL21753935

Nc1ccc(Cc2ccc(N)c(C(=O)O)c2)cc1C(=O)O.P

nearest known ligand 0.96

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.96
CDC25B P30305 1/20 0.96
CASP6 P55212 1/20 0.96
RCE1 Q9Y256 1/20 0.96
KDM4E B2RXH2 5/20 0.61
MAPT P10636 3/20 0.61
GAA P10253 2/20 0.61
HPGD P15428 1/20 0.61
ALOX15 P16050 1/20 0.61
TSHR P16473 1/20 0.61
HSD17B10 Q99714 1/20 0.61
KLKB1 P03952 1/20 0.60
CTSB P07858 1/20 0.60
MMP9 P14780 1/20 0.60
DNMT1 P26358 1/20 0.60
DNMT3B Q9UBC3 1/20 0.60
DNMT3L Q9UJW3 1/20 0.60
DNMT3A Q9Y6K1 1/20 0.60
KMT2A Q03164 3/20 0.59
GFER P55789 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29861837 0.98 ALDH1A1 (1.00) ALDH1A1CDC25BCASP6RCE1KDM4E
SCHEMBL107442 0.98 ALDH1A1 (1.00) ALDH1A1CDC25BCASP6RCE1KDM4E
SCHEMBL29832194 0.98 ALDH1A1 (1.00) ALDH1A1CDC25BCASP6RCE1KDM4E
Ammonia Solution, Strong SCHEMBL8509203 0.96 ALDH1A1 (0.96) ALDH1A1CDC25BCASP6RCE1KDM4E
SCHEMBL2131857 0.91 ALDH1A1 (0.86) ALDH1A1CDC25BCASP6RCE1KDM4E
SCHEMBL4989005 0.91 ALDH1A1 (0.86) ALDH1A1CDC25BCASP6RCE1KDM4E
SCHEMBL25170829 0.86 ALDH1A1 (0.78) ALDH1A1CDC25BCASP6RCE1KDM4E
SCHEMBL30291197 0.86 ALDH1A1 (0.78) ALDH1A1CDC25BCASP6RCE1KDM4E
SCHEMBL19419446 0.84 ALDH1A1 (0.75) ALDH1A1CDC25BCASP6RCE1KDM4E
SCHEMBL14080949 0.84 ALDH1A1 (0.75) ALDH1A1CDC25BCASP6RCE1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020040347-A1 POLYIMIDE FILM HAVING IMPROVED ALKALI RESISTANCE AND METHOD FOR MANUFACTURING SAME 에스케이씨코오롱피아이 주식회사 2020-02-27 WO claimed
WO-2020040347-A1 POLYIMIDE FILM HAVING IMPROVED ALKALI RESISTANCE AND METHOD FOR MANUFACTURING SAME 에스케이씨코오롱피아이 주식회사 2020-02-27 WO disclosed