Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.79 |
| ▸ | GAA | P10253 | 1/20 | 0.79 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | FDPS | P14324 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | SNCA | P37840 | 2/20 | 0.56 |
| ▸ | ACHE | P22303 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.53 |
| ▸ | APP | P05067 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3967422 | 0.95 | KDM4E (0.71) | KDM4EKMT2AGAAPOLBMEN1 | |
| SCHEMBL3967425 | 0.95 | KDM4E (0.71) | KDM4EKMT2AGAAPOLBMEN1 | |
| SCHEMBL17223787 | 0.92 | KDM4E (0.86) | KDM4EKMT2AGAAPOLBMEN1 | |
| SCHEMBL17223789 | 0.92 | KDM4E (0.86) | KDM4EKMT2AGAAPOLBMEN1 | |
| Cinametic Acid SCHEMBL29926813 | 0.89 | KDM4E (0.80) | KDM4EKMT2AGAAPOLBFDPS | |
| Cinametic Acid SCHEMBL555131 | 0.89 | KDM4E (0.80) | KDM4EKMT2AGAAPOLBFDPS | |
| SCHEMBL28457832 | 0.89 | KDM4E (0.80) | KDM4EKMT2AGAAPOLBMEN1 | |
| SCHEMBL30786821 | 0.89 | KDM4E (0.80) | KDM4EKMT2AGAAPOLBMEN1 | |
| SCHEMBL28899005 | 0.89 | KDM4E (0.73) | KDM4EKMT2AGAAPOLBMEN1 | |
| Cinametic Acid SCHEMBL11681943 | 0.89 | KDM4E (0.80) | KDM4EKMT2AGAAPOLBFDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10568889-B2 | Prostaglandin receptor EP2 antagonists, derivatives, compositions, and uses related thereto | EMORY UNIVERSITY (US) | 2020-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10568889-B2 | Prostaglandin receptor EP2 antagonists, derivatives, compositions, and uses related thereto | PTGER2, PTGES2, PTGER1 | KDM4E 3087/4885KMT2A 2414/4885GAA 4798/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.