Cinametic Acid

Cinametic Acid

SCHEMBL555131

COc1cc(/C=C/C(=O)O)ccc1OCCO

nearest known ligand 0.80

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.80
GAA P10253 1/20 0.78
KMT2A Q03164 1/20 0.78
ALDH1A1 P00352 2/20 0.73
HPGD P15428 1/20 0.73
ALOX15 P16050 1/20 0.73
MAPK1 P28482 1/20 0.73
SMN1; SMN2 Q16637 1/20 0.73
HSD17B10 Q99714 1/20 0.73
SNCA P37840 2/20 0.70
FDPS P14324 3/20 0.68
ACHE P22303 4/20 0.67
APP P05067 2/20 0.66
CA12 O43570 1/20 0.61
CA1 P00915 1/20 0.61
CA2 P00918 1/20 0.61
CA3 P07451 1/20 0.61
PKM P14618 1/20 0.61
CSNK2A2 P19784 1/20 0.61
CA4 P22748 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cinametic Acid SCHEMBL11681943 1.00 KDM4E (0.80) KDM4EGAAKMT2AALDH1A1HPGD
Cinametic Acid SCHEMBL29926813 1.00 KDM4E (0.80) KDM4EGAAKMT2AALDH1A1HPGD
SCHEMBL14229893 0.93 KDM4E (0.86) KDM4EGAAKMT2AALDH1A1HPGD
SCHEMBL6879248 0.92 KDM4E (0.76) KDM4EGAAKMT2AALDH1A1HPGD
SCHEMBL13168863 0.92 KDM4E (0.84) KDM4EGAAKMT2AALDH1A1HPGD
SCHEMBL17223787 0.91 KDM4E (0.86) KDM4EGAAKMT2AALDH1A1HPGD
SCHEMBL17223789 0.91 KDM4E (0.86) KDM4EGAAKMT2AALDH1A1HPGD
SCHEMBL7552212 0.91 KDM4E (0.74) KDM4EGAAKMT2AALDH1A1HPGD
SCHEMBL8410643 0.91 KDM4E (0.74) KDM4EGAAKMT2AALDH1A1HPGD
SCHEMBL13168868 0.90 KDM4E (0.82) KDM4EGAAKMT2AALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
WO-2011124227-A1 BIOCIDAL ACID-ADJUSTED POLYMER WITH POLYPROPYLENE VESTERGAARD FRANDSEN SA (CH) 2011-10-13 WO claimed
WO-2011124228-A1 A BIOCIDAL POLYOLEFIN YARN WITH 3-12 FILAMENTS VESTERGAARD FRANDSEN SA (CH) 2011-10-13 WO claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
US-20220047505-A1 Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration STI PHARMA, LLC (US) 2022-02-17 US disclosed
EP-3752201-A1 SUSPENSION OF NANOSCALE, ORGANIC PARTICLES AND PROCESS FOR PRODUCTION THEREOF Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) 2020-12-23 EP disclosed
US-10689330-B2 Amino acid derivatives and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2020-06-23 US disclosed
US-20200165192-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2020-05-28 US disclosed
US-10550072-B2 Amino acid derivatives and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2020-02-04 US disclosed
US-10463611-B2 Controlled absorption water-soluble pharmaceutically active organic compound formulation for once-daily administration STI PHARMA, LLC (US) 2019-11-05 US disclosed
US-20060172983-A1 Functionalized drugs and polymers derived therefrom BEZWADA BIOMEDICAL, LLC (US) 2006-08-03 US disclosed
CN-1523980-A Pharmaceutical formulations containing an active dispersed in a matrix ��̹��ҽҩ��˾ 2004-08-25 CN disclosed
US-20040058896-A1 Pharmaceutical preparation comprising an active dispersed on a matrix ASTRAZENECA AB (SE) 2004-03-25 US disclosed
EP-1341527-A1 PHARMACEUTICAL PREPARATION COMPRISING AN ACTIVE DISPERSED ON A MATRIX ALTANA Pharma AG (DE) 2003-09-10 EP disclosed
WO-2002045693-A1 PHARMACEUTICAL PREPARATION COMPRISING AN ACTIVE DISPERSED ON A MATRIX ALTANA PHARMA AG (DE) 2002-06-13 WO disclosed
CN-1201199-A Eight-queen stereo digital-image programming method and use for software library programming computor thereof WU ZONGSHENG (CN) 1998-12-09 CN disclosed
US-4053415-A UNSATURATED POLYESTER ETHER HAVING A PHOTOCROSSLINKABLE MOIETY FUJI PHOTO FILM CO., LTD. (JA) 1977-10-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10550072-B2 Amino acid derivatives and absorbable polymers therefrom SRRM2, SLC7A1, BCAT2 KDM4E 2679/4885GAA 2510/4885KMT2A 1431/4885
US-10689330-B2 Amino acid derivatives and absorbable polymers therefrom SRRM2, SLC7A1, BCAT2 KDM4E 2679/4885GAA 2510/4885KMT2A 1431/4885
US-20060172983-A1 Functionalized drugs and polymers derived therefrom OGFR, LOX, OPRM1 KDM4E 1584/4885GAA 804/4885KMT2A 3676/4885
US-20200165192-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM SRRM2, SLC7A1, BCAT2 KDM4E 2679/4885GAA 2510/4885KMT2A 1431/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.