Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | GLA | P06280 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | RAD52 | P43351 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | BCHE | P06276 | 6/20 | 0.61 |
| ▸ | ACHE | P22303 | 6/20 | 0.61 |
| ▸ | TERT | O14746 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.57 |
| ▸ | TOP2A | P11388 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14850990 | 0.82 | TLR9 (0.59) | KMT2ALMNAKDM4EGAANPC1 | |
| SCHEMBL14842148 | 0.81 | KMT2A (0.57) | KMT2ALMNAKDM4EGAANPC1 | |
| SCHEMBL24733471 | 0.80 | ACP1 (0.47) | KMT2ALMNAKDM4EGAANPC1 | |
| SCHEMBL29976948 | 0.80 | ACP1 (0.47) | KMT2ALMNAKDM4EGAANPC1 | |
| SCHEMBL14850945 | 0.79 | KDM4E (0.54) | KMT2ALMNAKDM4EGAANPC1 | |
| SCHEMBL4726553 | 0.78 | NPSR1 (1.00) | KMT2ALMNAKDM4EGAANPC1 | |
| SCHEMBL4088578 | 0.77 | CYP1A2 (0.72) | KMT2ALMNAPOLBNPSR1MAPT | |
| SCHEMBL20801391 | 0.77 | SLC2A1 (0.48) | BCHEACHEALDH1A1SLC2A1 | |
| SCHEMBL213949 | 0.76 | KCNH3 (0.46) | KMT2ALMNAKDM4EGAANPC1 | |
| SCHEMBL14233268 | 0.76 | TLR9 (0.64) | KMT2ALMNANPSR1MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2763677-B1 | NOVEL IMIDAZOLE QUINOLINE-BASED IMMUNE SYSTEM MODULATORS | JANUS BIOTHERAPEUTICS INC (US) | 2020-02-26 | — | — | EP | disclosed |