⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15548436 | 0.82 | — | — | |
| SCHEMBL3953922 | 0.82 | — | — | |
| SCHEMBL2019602 | 0.79 | — | — | |
| SCHEMBL10434860 | 0.78 | — | — | |
| SCHEMBL28222967 | 0.78 | — | — | |
| SCHEMBL16466483 | 0.76 | — | — | |
| SCHEMBL4921190 | 0.76 | — | — | |
| SCHEMBL19691223 | 0.76 | — | — | |
| SCHEMBL3927353 | 0.73 | — | — | |
| SCHEMBL7751515 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110437205-A | Pyridine alkenyl piperidine derivative and application thereof | GUANGDONG HEC PHARMACEUTICAL | 2019-11-12 | — | — | CN | disclosed |
| CN-110366550-A | Benzoisothiazole, isothiazolo [3,4-b ] pyridine, quinazoline, phthalazine, pyrido [2,3-d ] pyridazine and pyrido [2,3-d ] pyrimidine derivatives as KRAS G12C inhibitors for the treatment of lung, pancreatic or colorectal cancer | 美国安进公司 | 2019-10-22 | — | — | CN | disclosed |
| CN-109180670-A | Imino group thiadiazine dioxide derivative and application thereof | 广东东阳光药业有限公司 | 2019-01-11 | — | — | CN | disclosed |
| EP-3191112-A2 | DIPEPTIDYL KETOAMIDE COMPOUNDS AND THEIR USE FOR THE TREATMENT AND/OR PREVENTION OF FAT ACCUMULATION | LANDSTEINER GENMED, S.L. (ES) | 2017-07-19 | — | — | EP | disclosed |
| WO-2016038040-A2 | DIPEPTIDYL KETOAMIDE COMPOUNDS AND THEIR USE FOR THE TREATMENT AND/OR PREVENTION OF FAT ACCUMULATION | LANDSTEINER GENMED, S.L. (ES) | 2016-03-17 | — | — | WO | disclosed |
| CN-105228996-A | Tetrahydroisoquinolines containing substituted azoles as factor xia inhibitors | BRISTOL MYERS SQUIBB CO | 2016-01-06 | — | — | CN | disclosed |
| CN-104718188-A | N-substituted benzamides and their use in the treatment of pain | GENENTECH INC | 2015-06-17 | — | — | CN | disclosed |
| CN-104487433-A | Triazolone compounds as mpges-1 inhibitors | GLENMARK PHARMACEUTICALS SA | 2015-04-01 | — | — | CN | disclosed |
| CN-104059058-A | Compositions and methods for controlling nematodes | MONSANTO TECHNOLOGY LLC | 2014-09-24 | — | — | CN | disclosed |
| CN-104054719-A | Compositions And Methods For Controlling Nematodes | MONSANTO TECHNOLOGY LLC | 2014-09-24 | — | — | CN | disclosed |
| EP-2519522-A2 | SUBSTITUTED IMIDAZOPYRIDINYL-AMINOPYRIDINE COMPOUNDS | ArQule, Inc. (US) | 2012-11-07 | — | — | EP | disclosed |
| US-20110172203-A1 | Substituted Imidazopyridinyl-Aminopyridine Compounds | ARQULE, INC. (US) | 2011-07-14 | — | — | US | disclosed |
| WO-2011082270-A2 | SUBSTITUTED IMIDAZOPYRIDINYL-AMINOPYRIDINE COMPOUNDS | ARQULE. INC. (US) | 2011-07-07 | — | — | WO | disclosed |
| US-20080051419-A1 | AMINE DERIVATIVES USEFUL AS ANTICANCER AGENTS | PFIZER INC. | 2008-02-28 | — | — | US | disclosed |