⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15826452 | 0.87 | — | — | |
| SCHEMBL21757451 | 0.87 | — | — | |
| SCHEMBL23714921 | 0.86 | TSHR (0.32) | — | |
| SCHEMBL21757398 | 0.86 | TSHR (0.30) | — | |
| SCHEMBL21757410 | 0.84 | — | — | |
| SCHEMBL15826684 | 0.84 | NPC1 (0.44) | — | |
| SCHEMBL15825812 | 0.84 | NPC1 (0.44) | — | |
| SCHEMBL20713619 | 0.80 | — | — | |
| SCHEMBL14076285 | 0.76 | NCF1 (0.50) | — | |
| SCHEMBL13162816 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117015540-A | Thiophene compound and application thereof | 南京明德新药研发有限公司 | 2023-11-07 | — | — | CN | disclosed |
| CN-114507244-B | Imidazo thiazole compound, pharmaceutical composition and application thereof | 广州市恒诺康医药科技有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-109369635-B | Compound or pharmaceutically acceptable salt thereof, application thereof and pharmaceutical composition | 赛克里翁治疗有限公司 | 2023-06-30 | — | — | CN | disclosed |
| US-10925283-B2 | Microbiocidal phenylamidine derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2021-02-23 | — | — | US | disclosed |
| US-20200060275-A1 | MICROBIOCIDAL PHENYLAMIDINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2020-02-27 | — | — | US | disclosed |
| CN-110475777-A | For treating and preventing new pyrido [2,3-b] benzazolyl compounds of bacterium infection | HOFFMANN LA ROCHE | 2019-11-19 | — | — | CN | disclosed |
| CN-110312719-A | Imidazopyrrolopyridines as JAK Family Kinase Inhibitors | 詹森药业有限公司 | 2019-10-08 | — | — | CN | disclosed |
| CN-110088105-A | The micromolecular inhibitor of JAK family kinase | 詹森药业有限公司 | 2019-08-02 | — | — | CN | disclosed |
| CN-109863140-A | 3- oxo -2,6- diphenyl -2,3- dihydrogen dazin -4- formamide | 拜耳医药股份有限公司 | 2019-06-07 | — | — | CN | disclosed |
| CN-106103434-B | Tetrahydropyridine and pyrimidine compound or its salt | 大鹏药品工业株式会社 | 2019-05-10 | — | — | CN | disclosed |
| CN-109422749-A | A kind of pyrimidinedione derivative inhibiting monocarboxylate transporter | 重庆医药工业研究院有限责任公司 | 2019-03-05 | — | — | CN | disclosed |