Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 15/20 | 0.74 |
| ▸ | IMPDH1 | P20839 | 3/20 | 0.65 |
| ▸ | AAK1 | Q2M2I8 | 5/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6639762 | 0.90 | IMPDH2 (0.68) | IMPDH2IMPDH1AAK1 | |
| SCHEMBL14518599 | 0.87 | IMPDH2 (0.68) | IMPDH2IMPDH1AAK1 | |
| SCHEMBL25579071 | 0.83 | AAK1 (0.64) | IMPDH2IMPDH1AAK1 | |
| SCHEMBL14518602 | 0.83 | IMPDH2 (0.83) | IMPDH2IMPDH1AAK1 | |
| SCHEMBL14518615 | 0.82 | IMPDH2 (0.74) | IMPDH2IMPDH1AAK1 | |
| SCHEMBL16416663 | 0.82 | IMPDH2 (0.61) | IMPDH2IMPDH1AAK1 | |
| SCHEMBL5531405 | 0.81 | AAK1 (0.75) | IMPDH2IMPDH1AAK1 | |
| SCHEMBL6170236 | 0.81 | AAK1 (0.68) | IMPDH2IMPDH1AAK1 | |
| SCHEMBL1616816 | 0.81 | AAK1 (0.68) | IMPDH2IMPDH1AAK1 | |
| SCHEMBL6172224 | 0.81 | IMPDH2 (0.89) | IMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3902798-B1 | N-(4-(OXAZOL-5-YL)PHENYL)CHROMANE-3-CARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS STIMULATORS OF THE PRODUCTION OF RETINAL PRECURSOR CELLS FOR THE TREATMENT OF NEURORETINAL DISEASES | ENDOGENA THERAPEUTICS INC (US) | 2023-12-20 | — | — | EP | disclosed |
| EP-3215509-B1 | SUBSTITUTED PYRROLO[1,2-A]PYRIMIDINES AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS | LYSOSOMAL THERAPEUTICS INC (US) | 2020-02-26 | — | — | EP | disclosed |