SCHEMBL21758086

SCHEMBL21758086

CCC(CC)CNc1ccc(N)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.37
MAOB P27338 1/20 0.37
APP P05067 1/20 0.37
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
CYP3A4 P08684 4/20 0.35
ALDH1A1 P00352 3/20 0.35
L3MBTL1 Q9Y468 3/20 0.35
TSHR P16473 3/20 0.35
TDP1 Q9NUW8 3/20 0.35
MAPT P10636 3/20 0.35
CYP1A2 P05177 2/20 0.35
TP53 P04637 1/20 0.35
HSP90AA1 P07900 1/20 0.35
THRB P10828 1/20 0.35
ALOX15 P16050 1/20 0.35
CASP1 P29466 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21799458 0.82 ALDH1A1 (0.39) MAOAMAOBAPPCA12CA1
SCHEMBL2878804 0.80 MAPT (0.43) APPCA12CA1CA2CA9
SCHEMBL1926209 0.78 CA12 (0.42) MAOAMAOBAPPCA12CA1
SCHEMBL11046011 0.78 MAPT (0.48) CYP3A4ALDH1A1L3MBTL1TSHRTDP1
SCHEMBL21799640 0.77 MAPT (0.44) CYP3A4ALDH1A1TDP1MAPTCYP1A2
SCHEMBL29922565 0.77 MAPT (0.44) CYP3A4ALDH1A1TDP1MAPTCYP1A2
SCHEMBL11480947 0.77 SPHK1 (0.38) MAOAMAOBAPPCA1CA2
Hydrochloric Acid SCHEMBL27686456 0.77 CA12 (0.41) MAOAMAOBAPPCA12CA1
SCHEMBL1847030 0.76 ALDH1A1 (0.50) CYP3A4ALDH1A1L3MBTL1TSHRTDP1
SCHEMBL5155005 0.76 MAPT (0.43) MAOAMAOBAPPCA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3623398-B1 RESIN COMPOSITION COMPRISING A MODIFIED BLOCK COPOLYMER AND METHOD FOR PRODUCING MODIFIED BLOCK COPOLYMER ASAHI CHEMICAL IND (JP) 2024-08-28 EP disclosed
CN-110603273-B Modified block copolymer, method for producing modified block copolymer, and resin composition 旭化成株式会社 2022-10-14 CN disclosed
US-11124593-B2 Modified block copolymer, method for producing modified block copolymer, and resin composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2021-09-21 US disclosed
US-20200199282-A1 Modified Block Copolymer, Method for Producing Modified Block Copolymer, and Resin Composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2020-06-25 US disclosed
EP-3623398-A1 MODIFIED BLOCK COPOLYMER, METHOD FOR PRODUCING MODIFIED BLOCK COPOLYMER, AND RESIN COMPOSITION Asahi Kasei Kabushiki Kaisha (JP) 2020-03-18 EP disclosed
WO-2020040089-A1 LIQUID CRYSTAL ALIGNMENT AGENT, PRODUCTION METHOD THEREOF, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT 日産化学株式会社 2020-02-27 WO disclosed
CN-110603273-A Modified block copolymer, method for producing modified block copolymer, and resin composition 旭化成株式会社 2019-12-20 CN disclosed
CN-103641794-B Sulfonium compound and application thereof 维斯塔实验室有限公司 2016-09-21 CN disclosed
CN-101460157-B protein aggregation inhibitors WISTA LABORATORIES LTD. (SG) 2015-09-02 CN disclosed
CN-103735554-A Inhibitors of protein aggregation WISTA LAB LTD 2014-04-23 CN disclosed
CN-103641794-A Sulfonium compounds and their use WISTA LAB LTD 2014-03-19 CN disclosed
CN-101460222-B Sulfonium compounds and their use WISTA LAB LTD 2013-12-04 CN disclosed
CN-101460157-A Protein aggregation inhibitors WISTA LAB LTD (SG) 2009-06-17 CN disclosed
CN-101460222-A Sulfonium compounds and their use WISTA LAB LTD (SG) 2009-06-17 CN disclosed