Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 19/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 10/20 | 0.68 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2174199 | 0.89 | GCK (0.67) | GCKKCNH2DRD2DRD3 | |
| SCHEMBL17933976 | 0.89 | GCK (0.64) | GCKKCNH2 | |
| SCHEMBL2172409 | 0.87 | GCK (0.58) | GCKKCNH2 | |
| SCHEMBL2898939 | 0.86 | GCK (0.53) | GCKKCNH2 | |
| SCHEMBL4966753 | 0.85 | GCK (0.62) | GCKKCNH2DRD2DRD3 | |
| SCHEMBL2173208 | 0.84 | GCK (0.55) | GCKKCNH2 | |
| SCHEMBL2174783 | 0.83 | GCK (0.54) | GCKKCNH2 | |
| SCHEMBL2655454 | 0.81 | GCK (1.00) | GCKKCNH2 | |
| SCHEMBL2655031 | 0.81 | GCK (0.75) | GCKKCNH2 | |
| SCHEMBL2173188 | 0.81 | GCK (1.00) | GCKKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080300412-A1 | Chemical Process for the Preparation of an Amido-Phenoxybenzoic Acid Compound | ASTRAZENECA AB (SE) | 2008-12-04 | — | — | US | claimed |
| US-7973178-B2 | Chemical process for the preparation of an amido-phenoxybenzoic acid compound | ASTRAZENECA AB (SE) | 2011-07-05 | — | — | US | disclosed |
| US-20080300412-A1 | Chemical Process for the Preparation of an Amido-Phenoxybenzoic Acid Compound | ASTRAZENECA AB (SE) | 2008-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080300412-A1 | Chemical Process for the Preparation of an Amido-Phenoxybenzoic Acid Compound | GCK, HK1, PCK1 | GCK 1/4885KCNH2 683/4885DRD2 4004/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.