SCHEMBL2175889

SCHEMBL2175889

CCCCCCCCCCCCCCCCCSSCCCCCCCCCCCCCCCCC

nearest known ligand 0.57

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.57
THRB P10828 2/20 0.57
HSD17B10 Q99714 2/20 0.44
CES2 O00748 1/20 0.44
CTSL P07711 1/20 0.44
CTSB P07858 1/20 0.44
GMNN O75496 1/20 0.44
TP53 P04637 1/20 0.44
POLB P06746 1/20 0.44
MAPT P10636 1/20 0.44
CYP2C9 P11712 1/20 0.44
BLM P54132 1/20 0.44
DNM1 Q05193 7/20 0.43
CA2 P00918 1/20 0.42
ALDH1A1 P00352 2/20 0.42
LMNA P02545 2/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
SLC22A1 O15245 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4313208 1.00 TSHR (0.57) TSHRTHRBHSD17B10CES2CTSL
SCHEMBL11629534 1.00 TSHR (0.57) TSHRTHRBHSD17B10CES2CTSL
SCHEMBL10946121 1.00 TSHR (0.57) TSHRTHRBHSD17B10CES2CTSL
SCHEMBL10949090 1.00 TSHR (0.57) TSHRTHRBHSD17B10CES2CTSL
SCHEMBL1220054 1.00 TSHR (0.57) TSHRTHRBHSD17B10CES2CTSL
SCHEMBL9330272 1.00 TSHR (0.57) TSHRTHRBHSD17B10CES2CTSL
SCHEMBL1221777 1.00 TSHR (0.57) TSHRTHRBHSD17B10CES2CTSL
SCHEMBL867481 1.00 TSHR (0.57) TSHRTHRBHSD17B10CES2CTSL
SCHEMBL9329131 1.00 TSHR (0.57) TSHRTHRBHSD17B10CES2CTSL
SCHEMBL20634256 1.00 TSHR (0.57) TSHRTHRBHSD17B10CES2CTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2142485-B1 METALLIC SURFACE ENHANCEMENT MACDERMID ENTHONE INC (US) 2019-07-24 EP claimed
EP-3027787-A2 ORGANIC DISULFIDE BASED CORROSION INHIBITORS Ecolab USA Inc. (US) 2016-06-08 EP claimed
US-9238588-B2 Organic disulfide based corrosion inhibitors Ecolab USA, Inc. (US) 2016-01-19 US claimed
US-20150037202-A1 ORGANIC DISULFIDE BASED CORROSION INHIBITORS NORRIS RODS, INC., 2015-02-05 US claimed
US-8703243-B2 Anti-tarnish coatings ENTHONE INC. (US) 2014-04-22 US claimed
US-20120175022-A1 ANTI-TARNISH COATINGS ENTHONE INC. (US) 2012-07-12 US claimed
US-7972655-B2 Anti-tarnish coatings ENTHONE INC. (US) 2011-07-05 US claimed
US-20100291303-A1 ANTI-TARNISH COATINGS ENTHONE INC. (US) 2010-11-18 US claimed
EP-2220009-A1 ANTI-TARNISH COATING Enthone, Inc. (US) 2010-08-25 EP claimed
EP-2142485-A1 METALLIC SURFACE ENHANCEMENT Enthone, Inc. (US) 2010-01-13 EP claimed
WO-2009066080-A2 ARRAY NANOBIODESIGN LIMITED (GB) 2009-05-28 WO claimed
WO-2009067446-A1 ANTI-TARNISH COATING ENTHONE INC. (US) 2009-05-28 WO claimed
WO-2008131206-A1 METALLIC SURFACE ENHANCEMENT ENTHONE INC. (US) 2008-10-30 WO claimed
CN-105431571-B Organic disulfide-based corrosion inhibitors 艺康美国股份有限公司 2020-03-06 CN disclosed
EP-2142485-B1 METALLIC SURFACE ENHANCEMENT MACDERMID ENTHONE INC (US) 2019-07-24 EP disclosed
US-20180219160-A1 BENZOBIS(THIADIAZOLE) DERIVATIVE, INK COMPRISING THE SAME, AND ORGANIC ELECTRONIC DEVICE USING THE SAME UBE INDUSTRIES, LTD. (JP) 2018-08-02 US disclosed
EP-2142485-A1 METALLIC SURFACE ENHANCEMENT Enthone, Inc. (US) 2010-01-13 EP disclosed
WO-2009066080-A2 ARRAY NANOBIODESIGN LIMITED (GB) 2009-05-28 WO disclosed
WO-2009067446-A1 ANTI-TARNISH COATING ENTHONE INC. (US) 2009-05-28 WO disclosed
WO-2008131206-A1 METALLIC SURFACE ENHANCEMENT ENTHONE INC. (US) 2008-10-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180219160-A1 BENZOBIS(THIADIAZOLE) DERIVATIVE, INK COMPRISING THE SAME, AND ORGANIC ELECTRONIC DEVICE USING THE SAME IKZF3, HELZ, TEC TSHR 2400/4885THRB 3185/4885HSD17B10 3674/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.