Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 3/20 | 0.55 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.55 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 11/20 | 0.40 |
| ▸ | SRC | P12931 | 11/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 10/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 10/20 | 0.40 |
| ▸ | PRKDC | P78527 | 10/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 9/20 | 0.40 |
| ▸ | ABL1 | P00519 | 9/20 | 0.40 |
| ▸ | EGFR | P00533 | 9/20 | 0.40 |
| ▸ | HCK | P08631 | 9/20 | 0.40 |
| ▸ | MTOR | P42345 | 9/20 | 0.40 |
| ▸ | EPHB4 | P54760 | 9/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 9/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 9/20 | 0.40 |
| ▸ | RET | P07949 | 4/20 | 0.40 |
| ▸ | TEK | Q02763 | 2/20 | 0.39 |
| ▸ | PI4KA | P42356 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6364419 | 0.84 | PIK3CD (0.51) | ADORA2AADORA2BADORA1KDRSRC | |
| SCHEMBL19775103 | 0.84 | ADORA2A (0.56) | ADORA2AADORA2BADORA1ADORA3KDR | |
| SCHEMBL22381516 | 0.83 | PI4KB (0.41) | ADORA2AADORA2BADORA1KDRSRC | |
| SCHEMBL16236571 | 0.82 | ADORA2A (0.55) | ADORA2AADORA2BADORA1ADORA3KDR | |
| SCHEMBL20058786 | 0.82 | PIK3CB (0.43) | ADORA2AADORA2BADORA1KDRSRC | |
| SCHEMBL19187882 | 0.79 | KDR (0.40) | KDRSRCPIK3CBPIK3CGPRKDC | |
| SCHEMBL24222133 | 0.76 | SRC (0.38) | ADORA2AADORA2BADORA1KDRSRC | |
| SCHEMBL18874423 | 0.76 | PIK3CG (0.55) | ADORA2AADORA2BADORA1KDRSRC | |
| SCHEMBL19711585 | 0.75 | ADORA2A (0.50) | ADORA2AADORA2BADORA1ADORA3SRC | |
| SCHEMBL21137166 | 0.74 | PARP1 (0.37) | ADORA2AADORA2BADORA1ADORA3SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220033431-A1 | Cyclic Di-Nucleotide Compounds as STING Agonists | MERCK SHARP & DOHME CORP. (US) | 2022-02-03 | — | — | US | disclosed |
| US-20220033406-A1 | CYCLOPENTYL NUCLEOSIDE ANALOGS AS ANTI-VIRALS | Janssen Pharmaceuticals, Inc. | 2022-02-03 | — | — | US | disclosed |
| US-20200062798-A1 | CYCLIC DI-NUCLEOTIDE COMPOUNDS AS STING AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2020-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220033406-A1 | CYCLOPENTYL NUCLEOSIDE ANALOGS AS ANTI-VIRALS | PNP, TYMP, HAVCR2 | ADORA2A 130/4885ADORA2B 292/4885ADORA1 137/4885 |
| US-20220033431-A1 | Cyclic Di-Nucleotide Compounds as STING Agonists | STING1, CGAS, IFNAR1 | ADORA2A 64/4885ADORA2B 132/4885ADORA1 32/4885 |
| US-20200062798-A1 | CYCLIC DI-NUCLEOTIDE COMPOUNDS AS STING AGONISTS | STING1, CGAS, IFNAR1 | ADORA2A 69/4885ADORA2B 144/4885ADORA1 36/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.