Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CB | P42338 | 10/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 10/20 | 0.43 |
| ▸ | PRKDC | P78527 | 10/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 9/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 9/20 | 0.43 |
| ▸ | KDR | P35968 | 13/20 | 0.42 |
| ▸ | SRC | P12931 | 12/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 9/20 | 0.42 |
| ▸ | ABL1 | P00519 | 9/20 | 0.42 |
| ▸ | EGFR | P00533 | 9/20 | 0.42 |
| ▸ | HCK | P08631 | 9/20 | 0.42 |
| ▸ | MTOR | P42345 | 9/20 | 0.42 |
| ▸ | EPHB4 | P54760 | 9/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | PI4KA | P42356 | 1/20 | 0.41 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6364419 | 0.87 | PIK3CD (0.51) | PIK3CBPIK3CGPRKDCPIK3CDPIK3CA | |
| SCHEMBL22381516 | 0.86 | PI4KB (0.41) | PIK3CBPIK3CGPRKDCPIK3CDPIK3CA | |
| SCHEMBL21758960 | 0.82 | ADORA2A (0.55) | PIK3CBPIK3CGPRKDCPIK3CDPIK3CA | |
| SCHEMBL19187882 | 0.78 | KDR (0.40) | PIK3CBPIK3CGPRKDCPIK3CDPIK3CA | |
| SCHEMBL19402563 | 0.77 | AHCY (0.39) | PIK3CBPIK3CGPRKDCPIK3CDPIK3CA | |
| SCHEMBL12966924 | 0.76 | RET (0.39) | PIK3CBPIK3CGPRKDCPIK3CDPIK3CA | |
| SCHEMBL29324056 | 0.76 | KDR (0.39) | PIK3CBPIK3CGPRKDCPIK3CDPIK3CA | |
| SCHEMBL14816754 | 0.76 | RET (0.39) | PIK3CBPIK3CGPRKDCPIK3CDPIK3CA | |
| SCHEMBL24222133 | 0.76 | SRC (0.38) | PIK3CBPIK3CGPRKDCPIK3CDPIK3CA | |
| SCHEMBL6430725 | 0.75 | EIF2AK3 (0.46) | PI4KBADORA2AADORA1PI4KAPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2906579-B1 | 2'-CHLORO NUCLEOSIDE ANALOGS FOR HCV INFECTION | IDENIX PHARMACEUTICALS LLC (US) | 2018-04-18 | — | — | EP | disclosed |