SCHEMBL2175960

SCHEMBL2175960

CC1(C(=O)O)C(=O)OC1=O

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 5/20 0.34
TP53 P04637 4/20 0.34
CYP3A4 P08684 3/20 0.34
HIF1A Q16665 3/20 0.34
LMNA P02545 3/20 0.34
SMN1; SMN2 Q16637 3/20 0.34
NPC1 O15118 3/20 0.34
RAB9A P51151 3/20 0.34
CYP1A2 P05177 2/20 0.34
NFKB1 P19838 2/20 0.34
THPO P40225 2/20 0.34
GMNN O75496 2/20 0.34
MTOR P42345 2/20 0.34
BLM P54132 2/20 0.34
PMP22 Q01453 2/20 0.34
PPM1B O75688 1/20 0.34
PTPN1 P18031 1/20 0.34
PPP1CC P36873 1/20 0.34
TFPI2 P48307 1/20 0.34
PPP5C P53041 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20641871 0.70 TP53 (0.30) MAPK1TP53CYP3A4HIF1ALMNA
SCHEMBL16389848 0.69
SCHEMBL13296272 0.67 FFAR3 (0.41) MAPK1TP53CYP3A4HIF1ALMNA
SCHEMBL16389864 0.66 TP53 (0.31) MAPK1TP53CYP3A4HIF1ALMNA
SCHEMBL5119335 0.65 TP53 (0.42) MAPK1TP53CYP3A4HIF1ALMNA
SCHEMBL13515254 0.65 TP53 (0.42) MAPK1TP53CYP3A4HIF1ALMNA
SCHEMBL12110851 0.65 TP53 (0.42) MAPK1TP53CYP3A4HIF1ALMNA
SCHEMBL3903253 0.64 CDC25A (0.30)
SCHEMBL14880147 0.63 FFAR3 (0.31) PTPN1FFAR3
SCHEMBL14881961 0.63 FFAR3 (0.31) CYP3A4CYP1A2PTPN1TSHRFFAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7973122-B2 Polyamideimide compositions having multifunctional core structures GENERAL CABLE TECHNOLOGIES CORPORATION (US) 2011-07-05 US disclosed
US-20080160304-A1 Polyamideimide compositions having multifunctional core structures GENERAL CABLE TECHNOLOGIES 2008-07-03 US disclosed
US-20050282010-A1 Polyamideimide compositions having multifunctional core structures GENERAL CABLE TECHNOLOGIES CORPORATION 2005-12-22 US disclosed