Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20106142 | 0.89 | NTRK1 (0.59) | NTRK1JAK2 | |
| SCHEMBL21243824 | 0.87 | NTRK1 (0.69) | NTRK1JAK2 | |
| SCHEMBL20105863 | 0.87 | NTRK1 (0.69) | NTRK1JAK2 | |
| SCHEMBL20106459 | 0.87 | NTRK1 (0.69) | NTRK1JAK2 | |
| SCHEMBL21243827 | 0.84 | NTRK1 (0.65) | NTRK1JAK2 | |
| SCHEMBL20106510 | 0.84 | NTRK1 (0.65) | NTRK1JAK2 | |
| SCHEMBL23051018 | 0.81 | NTRK1 (0.79) | NTRK1JAK2 | |
| SCHEMBL7705201 | 0.81 | NTRK1 (0.73) | NTRK1JAK2 | |
| SCHEMBL21510423 | 0.80 | NTRK1 (0.61) | NTRK1JAK2 | |
| SCHEMBL17820785 | 0.78 | NTRK1 (0.71) | NTRK1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020038415-A1 | TROPOMYOSIN RECEPTOR KINASE (TRK) DEGRADATION COMPOUNDS AND METHODS OF USE | CULLGEN (SHANGHAI), INC. (CN) | 2020-02-27 | — | — | WO | disclosed |