⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25762557 | 0.82 | — | — | |
| SCHEMBL5792911 | 0.79 | — | — | |
| SCHEMBL25859218 | 0.71 | KDM4E (0.41) | — | |
| SCHEMBL21363734 | 0.71 | KDM4E (0.41) | — | |
| SCHEMBL19750189 | 0.71 | KDM4E (0.41) | — | |
| SCHEMBL1117927 | 0.71 | KDM4E (0.41) | — | |
| SCHEMBL21398619 | 0.71 | KDM4E (0.41) | — | |
| SCHEMBL16285870 | 0.71 | KDM4E (0.41) | — | |
| SCHEMBL21310426 | 0.71 | — | — | |
| SCHEMBL23766519 | 0.70 | P2RX7 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10874640-B2 | Substituted pyrrolizine compounds and uses thereof | GILEAD SCIENCES, INC. (US) | 2020-12-29 | — | — | US | disclosed |
| US-20200061024-A1 | SUBSTITUTED PYRROLIZINE COMPOUNDS AND USES THEREOF | GILEAD SCIENCES, INC. | 2020-02-27 | — | — | US | disclosed |