Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 20/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21760044 | 0.92 | CRBN (0.69) | CRBN | |
| SCHEMBL23535151 | 0.88 | CRBN (0.70) | CRBN | |
| SCHEMBL21759952 | 0.86 | CRBN (0.71) | CRBN | |
| SCHEMBL21759455 | 0.85 | CRBN (0.67) | CRBN | |
| SCHEMBL30128254 | 0.85 | CRBN (0.67) | CRBN | |
| SCHEMBL21855163 | 0.84 | CRBN (0.65) | CRBN | |
| SCHEMBL24186805 | 0.84 | CRBN (0.75) | CRBN | |
| SCHEMBL23915098 | 0.83 | CRBN (0.64) | CRBN | |
| SCHEMBL24046504 | 0.83 | CRBN (0.67) | CRBN | |
| SCHEMBL21759475 | 0.83 | CRBN (0.67) | CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020038415-A1 | TROPOMYOSIN RECEPTOR KINASE (TRK) DEGRADATION COMPOUNDS AND METHODS OF USE | CULLGEN (SHANGHAI), INC. (CN) | 2020-02-27 | — | — | WO | disclosed |