SCHEMBL21759952

SCHEMBL21759952

CC#Cc1ccc2c(c1)C(=O)N(C1CCC(=O)NC1=O)C2

nearest known ligand 0.71

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 20/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30569130 0.92 CRBN (0.69) CRBN
SCHEMBL24637376 0.92 CRBN (0.69) CRBN
SCHEMBL26270745 0.88 CRBN (0.64) CRBN
SCHEMBL23915098 0.88 CRBN (0.64) CRBN
SCHEMBL21855163 0.86 CRBN (0.65) CRBN
SCHEMBL21760436 0.86 CRBN (0.70) CRBN
SCHEMBL23535151 0.86 CRBN (0.70) CRBN
SCHEMBL24046504 0.85 CRBN (0.67) CRBN
SCHEMBL21759475 0.85 CRBN (0.67) CRBN
SCHEMBL21759455 0.85 CRBN (0.67) CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022068933-A1 COMPOUNDS AND METHODS OF TREATING DISEASES CULLGEN (SHANGHAI) , INC. (CN) 2022-04-07 WO disclosed
WO-2020038415-A1 TROPOMYOSIN RECEPTOR KINASE (TRK) DEGRADATION COMPOUNDS AND METHODS OF USE CULLGEN (SHANGHAI), INC. (CN) 2020-02-27 WO disclosed