Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL637539 | 0.78 | CYP1A2 (0.66) | ALOX12CYP1A2TDP1MAPK1PKM | |
| SCHEMBL21894538 | 0.76 | ALOX12 (0.59) | ALOX12CYP1A2TDP1MAPK1ALOX15 | |
| SCHEMBL21893409 | 0.73 | ALOX12 (0.56) | ALOX12CYP1A2TDP1MAPK1ALOX15 | |
| SCHEMBL13255816 | 0.73 | ALOX12 (0.56) | ALOX12CYP1A2TDP1MAPK1ALOX15 | |
| SCHEMBL6209906 | 0.72 | ALOX12 (0.54) | ALOX12CYP1A2TDP1MAPK1ALOX15 | |
| SCHEMBL21893779 | 0.72 | ALOX12 (0.54) | ALOX12CYP1A2TDP1MAPK1ALOX15 | |
| SCHEMBL10514418 | 0.72 | ALOX12 (0.54) | ALOX12CYP1A2TDP1MAPK1ALOX15 | |
| SCHEMBL9516847 | 0.71 | MAPK1 (0.59) | ALOX12CYP1A2TDP1MAPK1ALOX15 | |
| SCHEMBL10998420 | 0.71 | TDP1 (1.00) | ALOX12CYP1A2TDP1MAPK1PKM | |
| SCHEMBL9363424 | 0.69 | ALOX12 (0.51) | ALOX12CYP1A2TDP1MAPK1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023110138-A1 | INHIBITORS OF TRANSGLUTAMINASES | ZEDIRA GMBH (DE) | 2023-06-22 | — | — | WO | disclosed |
| WO-2023275333-A1 | INHIBITORS OF TRANSGLUTAMINASES | ZEDIRA GMBH (DE) | 2023-01-05 | — | — | WO | disclosed |
| WO-2023275336-A1 | INHIBITORS OF TRANSGLUTAMINASES | ZEDIRA GMBH (DE) | 2023-01-05 | — | — | WO | disclosed |
| EP-3842439-A1 | BICYCLIC HETEROAROMATIC RING DERIVATIVE | Kyorin Pharmaceutical Co., Ltd. (JP) | 2021-06-30 | — | — | EP | disclosed |
| WO-2020040104-A1 | BICYCLIC HETEROAROMATIC RING DERIVATIVE | 杏林製薬株式会社 | 2020-02-27 | — | — | WO | disclosed |