SCHEMBL21760735

SCHEMBL21760735

O=C(O)c1ccc2c(c1)c1ccccc1n2-c1ccccc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.69
ALDH1A1 P00352 4/20 0.60
L3MBTL1 Q9Y468 3/20 0.60
ATM Q13315 1/20 0.60
HPGD P15428 1/20 0.60
HSD17B10 Q99714 2/20 0.52
PTGER4 P35408 1/20 0.52
NPSR1 Q6W5P4 1/20 0.50
FOLH1 Q04609 2/20 0.49
FGFR1 P11362 1/20 0.48
GAA P10253 2/20 0.46
KMT2A Q03164 2/20 0.46
MEN1 O00255 1/20 0.46
USP2 O75604 1/20 0.46
MYC P01106 1/20 0.46
POLB P06746 1/20 0.46
HSPA1A P0DMV8 1/20 0.46
MAPT P10636 1/20 0.46
ALOX15 P16050 1/20 0.46
NR4A1 P22736 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31416092 1.00 KDM4E (0.69) KDM4EALDH1A1L3MBTL1ATMHPGD
SCHEMBL13018710 0.94 KDM4E (0.65) KDM4EALDH1A1L3MBTL1ATMHPGD
SCHEMBL31464191 0.90 KDM4E (0.60) KDM4EALDH1A1L3MBTL1ATMHPGD
SCHEMBL23948802 0.90 KDM4E (0.60) KDM4EALDH1A1L3MBTL1ATMHPGD
SCHEMBL13011123 0.90 KDM4E (0.60) KDM4EALDH1A1L3MBTL1ATMHPGD
SCHEMBL18687048 0.88 KDM4E (0.54) KDM4EALDH1A1L3MBTL1HPGDHSD17B10
SCHEMBL13300206 0.87 HPGD (0.59) KDM4EALDH1A1L3MBTL1ATMHPGD
SCHEMBL6313499 0.87 KDM4E (0.56) KDM4EALDH1A1L3MBTL1ATMHPGD
SCHEMBL23948765 0.87 KDM4E (0.56) KDM4EALDH1A1L3MBTL1ATMHPGD
SCHEMBL21760733 0.86 FOLH1 (0.62) KDM4EALDH1A1L3MBTL1ATMHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112125836-A Synthetic method of organic electro-optic material intermediate N-phenylcarbazole-3-carboxylic acid ethyl ester 濮阳惠成电子材料股份有限公司 2020-12-25 CN claimed
US-11637256-B2 Quantum dots with charge-transporting ligands NANOSYS, INC. (US) 2023-04-25 US disclosed
CN-115745988-A D-A-A type deep red fluorescent compound and synthetic method and application thereof 广州天赐高新材料股份有限公司 2023-03-07 CN disclosed
CN-112125836-A Synthetic method of organic electro-optic material intermediate N-phenylcarbazole-3-carboxylic acid ethyl ester 濮阳惠成电子材料股份有限公司 2020-12-25 CN disclosed
CN-112125836-A Synthetic method of organic electro-optic material intermediate N-phenylcarbazole-3-carboxylic acid ethyl ester 濮阳惠成电子材料股份有限公司 2020-12-25 CN disclosed
WO-2020040982-A1 QUANTUM DOTS WITH CHARGE-TRANSPORTING LIGANDS NANOSYS, INC. (US) 2020-02-27 WO disclosed
US-20200067006-A1 QUANTUM DOTS WITH CHARGE-TRANSPORTING LIGANDS NANOSYS, INC. (US) 2020-02-27 US disclosed