Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23948765 | 0.97 | KDM4E (0.56) | KDM4EL3MBTL1ATMALDH1A1HPGD | |
| SCHEMBL16271521 | 0.95 | KDM4E (0.55) | KDM4EL3MBTL1ATMALDH1A1HPGD | |
| SCHEMBL6313499 | 0.94 | KDM4E (0.56) | KDM4EL3MBTL1ATMALDH1A1HPGD | |
| Potassium Ion SCHEMBL6313935 | 0.91 | KDM4E (0.53) | KDM4EL3MBTL1ATMALDH1A1HPGD | |
| SCHEMBL31416092 | 0.90 | KDM4E (0.69) | KDM4EL3MBTL1ATMALDH1A1HPGD | |
| SCHEMBL21760735 | 0.90 | KDM4E (0.69) | KDM4EL3MBTL1ATMALDH1A1HPGD | |
| SCHEMBL23948389 | 0.88 | KDM4E (0.48) | KDM4EL3MBTL1ATMALDH1A1HPGD | |
| SCHEMBL13300206 | 0.87 | HPGD (0.59) | KDM4EL3MBTL1ATMALDH1A1HPGD | |
| SCHEMBL23948690 | 0.87 | KDM4E (0.47) | KDM4EL3MBTL1ATMALDH1A1HPGD | |
| SCHEMBL16271529 | 0.86 | KDM4E (0.47) | KDM4EL3MBTL1ATMALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210323963-A1 | Functional Materials Based on Stable Chemical Structure | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY | 2021-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210323963-A1 | Functional Materials Based on Stable Chemical Structure | TEAD4, TEAD2, TEAD1 | KDM4E 2817/4885L3MBTL1 1154/4885ATM 2872/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.