Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 3/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21761046 | 0.81 | SMN1; SMN2 (0.39) | SMN1; SMN2TSHRGLALMNAALDH1A1 | |
| SCHEMBL15822237 | 0.79 | HTR2A (0.38) | SMN1; SMN2TSHRGLAALDH1A1MAPT | |
| SCHEMBL21761043 | 0.78 | SMN1; SMN2 (0.38) | SMN1; SMN2TSHRGLALMNAALDH1A1 | |
| SCHEMBL23585316 | 0.78 | SMN1; SMN2 (0.40) | SMN1; SMN2TSHRGLALMNAALDH1A1 | |
| SCHEMBL21760774 | 0.77 | SMN1; SMN2 (0.40) | SMN1; SMN2TSHRGLALMNAALDH1A1 | |
| SCHEMBL23585513 | 0.72 | SMN1; SMN2 (0.36) | SMN1; SMN2TSHRGLALMNAALDH1A1 | |
| SCHEMBL23585393 | 0.72 | HTR2A (0.45) | SMN1; SMN2TSHRGLALMNAALDH1A1 | |
| SCHEMBL4073579 | 0.71 | SMN1; SMN2 (0.47) | SMN1; SMN2TSHRALDH1A1MAPTAR | |
| SCHEMBL21189843 | 0.71 | KDM4E (0.40) | SMN1; SMN2TSHRGLAALDH1A1MAPT | |
| SCHEMBL21761033 | 0.70 | SMN1; SMN2 (0.51) | SMN1; SMN2TSHRGLAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3842439-A1 | BICYCLIC HETEROAROMATIC RING DERIVATIVE | Kyorin Pharmaceutical Co., Ltd. (JP) | 2021-06-30 | — | — | EP | disclosed |
| WO-2020040104-A1 | BICYCLIC HETEROAROMATIC RING DERIVATIVE | 杏林製薬株式会社 | 2020-02-27 | — | — | WO | disclosed |