Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | F2RL3 | Q96RI0 | 7/20 | 0.33 |
| ▸ | PPOX | P50336 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23585579 | 0.86 | F2RL3 (0.34) | F2RL3 | |
| SCHEMBL21761020 | 0.80 | NPC1 (0.36) | MEN1MAPTKMT2AF2RL3 | |
| SCHEMBL21761011 | 0.76 | F2RL3 (0.35) | MAPTF2RL3 | |
| SCHEMBL21761041 | 0.76 | F2RL3 (0.39) | F2RL3 | |
| SCHEMBL8686099 | 0.75 | F2RL3 (0.40) | F2RL3 | |
| SCHEMBL34472205 | 0.74 | F2RL3 (0.40) | MEN1MAPTKMT2AF2RL3 | |
| SCHEMBL21760987 | 0.74 | ALDH1A1 (0.41) | MEN1MAPTPKMHTTKMT2A | |
| SCHEMBL21760998 | 0.73 | MAPK1 (0.36) | MEN1MAPTPKMHTTKMT2A | |
| SCHEMBL15349923 | 0.72 | F2RL3 (0.44) | KMT2AGAAF2RL3 | |
| SCHEMBL634381 | 0.72 | SSTR4 (0.40) | MEN1MAPTKMT2ACNR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3842439-A1 | BICYCLIC HETEROAROMATIC RING DERIVATIVE | Kyorin Pharmaceutical Co., Ltd. (JP) | 2021-06-30 | — | — | EP | disclosed |
| WO-2020040104-A1 | BICYCLIC HETEROAROMATIC RING DERIVATIVE | 杏林製薬株式会社 | 2020-02-27 | — | — | WO | disclosed |