Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 3/20 | 0.37 |
| ▸ | MAOB | P27338 | 6/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.36 |
| ▸ | STS | P08842 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 2/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22590849 | 0.92 | CNR1 (0.37) | MAOBCYP19A1MIF | |
| SCHEMBL22590855 | 0.86 | GLA (0.33) | GLAMAOBCYP19A1STSKDM4E | |
| SCHEMBL22590882 | 0.81 | MIF (0.40) | MAOBCYP19A1KDM4EHPGDMIF | |
| SCHEMBL21116158 | 0.81 | MIF (0.54) | GLAKDM4EALDH1A1GAAHPGD | |
| SCHEMBL22590756 | 0.79 | HPN (0.43) | GLAMAOBKDM4EALDH1A1GAA | |
| SCHEMBL21761558 | 0.78 | MIF (0.56) | GLAMAOBKDM4EALDH1A1GAA | |
| SCHEMBL18583398 | 0.75 | MIF (0.49) | GLAKDM4EALDH1A1GAAHPGD | |
| SCHEMBL21065582 | 0.74 | GPR55 (0.39) | MAOBCYP19A1KDM4EALDH1A1LMNA | |
| SCHEMBL22590761 | 0.74 | MAPT (0.40) | GLAMAOBSTSKDM4EALDH1A1 | |
| SCHEMBL18583393 | 0.73 | GLA (0.56) | GLAMAOBKDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11001576-B2 | Compounds for optically active devices | MERCK PATENT GMBH (DE) | 2021-05-11 | — | — | US | disclosed |
| US-20200062739-A1 | COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2020-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200062739-A1 | COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | PDE6C, PDE6A, PDE6D | GLA 247/4885MAOB 372/4885CYP19A1 1108/4885 |
| US-11001576-B2 | Compounds for optically active devices | PDE6C, PDE6A, PDE6D | GLA 247/4885MAOB 372/4885CYP19A1 1108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.