Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.48 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.47 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.45 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL349195 | 0.93 | MEN1 (0.56) | MEN1KMT2AHSD11B1HTTOPRM1 | |
| Iodomethane SCHEMBL3898463 | 0.89 | MEN1 (0.53) | MEN1KMT2AHSD11B1HTTOPRM1 | |
| SCHEMBL2481767 | 0.86 | AKR1C1 (0.58) | MEN1KMT2AHSD11B1HTTOPRM1 | |
| SCHEMBL1041983 | 0.86 | AKR1C1 (0.63) | MEN1KMT2AHSD11B1HTTAKR1C1 | |
| SCHEMBL1042494 | 0.84 | HDAC4 (0.62) | MEN1KMT2AHSD11B1HTTAKR1C1 | |
| SCHEMBL1038755 | 0.84 | HDAC4 (0.62) | MEN1KMT2AHSD11B1HTTAKR1C1 | |
| SCHEMBL1042365 | 0.84 | HDAC4 (0.62) | MEN1KMT2AHSD11B1HTTAKR1C1 | |
| SCHEMBL8110538 | 0.82 | AKR1C1 (0.68) | MEN1KMT2AHSD11B1AKR1C1HDAC4 | |
| SCHEMBL1626631 | 0.81 | ALDH1A1 (0.61) | MEN1KMT2AHSD11B1APOBEC3AAPOBEC3G | |
| SCHEMBL5765569 | 0.81 | MEN1 (0.50) | MEN1KMT2AHSD11B1HTTOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197879-B1 | NEW BICYCLIC DERIVATIVES HAVING BETA2 ADRENERGIC AGONIST AND M3 MUSCARINIC ANTAGONIST ACTIVITIES | ALMIRALL SA (ES) | 2020-02-26 | — | — | EP | disclosed |