Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 3/20 | 0.34 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | MITF | O75030 | 1/20 | 0.30 |
| ▸ | STAT3 | P40763 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31466768 | 0.82 | WEE1 (0.34) | FGFR1LMNASMN1; SMN2HPGD | |
| SCHEMBL31466967 | 0.81 | FGFR1 (0.37) | FGFR4FGFR1HTTNPSR1NPC1 | |
| SCHEMBL20943073 | 0.81 | FGFR2 (0.35) | FGFR4FGFR2FGFR1LMNASMN1; SMN2 | |
| SCHEMBL23328282 | 0.78 | FGFR1 (0.53) | FGFR4FGFR2FGFR1 | |
| SCHEMBL31466892 | 0.76 | FGFR1 (0.37) | FGFR1LMNASMN1; SMN2PDE1BHPGD | |
| SCHEMBL21761800 | 0.75 | PDE4A (0.33) | FGFR4FGFR2FGFR1PDE1B | |
| SCHEMBL16071547 | 0.74 | FGFR2 (0.53) | FGFR4FGFR2FGFR1 | |
| SCHEMBL31466891 | 0.70 | FGFR1 (0.37) | FGFR4FGFR2FGFR1 | |
| SCHEMBL16060872 | 0.69 | FGFR1 (0.47) | FGFR4FGFR2FGFR1 | |
| SCHEMBL20942985 | 0.68 | FGFR1 (0.39) | FGFR4FGFR2FGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020038458-A1 | CLASS OF FUSED RING TRIAZOLE COMPOUND, PREPARATION METHOD, AND USE | 如东凌达生物医药科技有限公司 | 2020-02-27 | — | — | WO | disclosed |