Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 8/20 | 0.37 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | FGFR4 | P22455 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31466768 | 0.90 | WEE1 (0.34) | FGFR1EGFRPDE4BPDE4APDE4C | |
| SCHEMBL31466778 | 0.82 | FGFR1 (0.45) | FGFR1EGFRFGFR4 | |
| SCHEMBL31466870 | 0.82 | FGFR1 (0.38) | FGFR1EGFRPDE4BPDE4APDE4C | |
| SCHEMBL31466999 | 0.82 | FGFR1 (0.43) | FGFR1FGFR4 | |
| SCHEMBL21761933 | 0.81 | FGFR4 (0.34) | FGFR1FGFR4NPC1ALDH1A1HTT | |
| SCHEMBL23328282 | 0.80 | FGFR1 (0.53) | FGFR1FGFR4 | |
| SCHEMBL31466892 | 0.80 | FGFR1 (0.37) | FGFR1NPC1MEN1KMT2ATLR9 | |
| SCHEMBL31466823 | 0.79 | PDE4A (0.36) | FGFR1EGFRPDE4BPDE4APDE4C | |
| SCHEMBL31466818 | 0.76 | FGFR1 (0.39) | FGFR1FGFR4NPC1MEN1KMT2A | |
| SCHEMBL31466859 | 0.74 | DHFR (0.41) | FGFR1EGFRFGFR4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025064567-A1 | TRICYCLIC PHENOLS FOR INHIBITION OF RAF KINASES | ENLIVEN INC. (US) | 2025-03-27 | — | — | WO | disclosed |