SCHEMBL21762017

SCHEMBL21762017

CSc1ccc2c(c1)CCCN([C@H](C)c1ccc3scnc3c1)C2

nearest known ligand 0.44

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
OGA O60502 16/20 0.44
HRH3 Q9Y5N1 1/20 0.33
PIK3CA P42336 2/20 0.32
MTOR P42345 2/20 0.32
HTR2A P28223 1/20 0.31
HTR2C P28335 1/20 0.31
HTR2B P41595 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21762233 1.00 OGA (0.44) OGAHRH3PIK3CAMTORHTR2A
SCHEMBL21762024 1.00 OGA (0.44) OGAHRH3PIK3CAMTORHTR2A
SCHEMBL21762016 0.88 OGA (0.49) OGAPIK3CAMTORHTR2AHTR2C
SCHEMBL21762195 0.88 OGA (0.49) OGAPIK3CAMTORHTR2AHTR2C
SCHEMBL21762023 0.88 OGA (0.49) OGAPIK3CAMTORHTR2AHTR2C
SCHEMBL21761873 0.86 OGA (0.46) OGAHRH3PIK3CAMTOR
SCHEMBL21761900 0.86 OGA (0.46) OGAHRH3PIK3CAMTOR
SCHEMBL21761861 0.86 OGA (0.46) OGAHRH3PIK3CAMTOR
SCHEMBL21753266 0.83 OGA (0.43) OGAHRH3PIK3CAMTOR
SCHEMBL21761862 0.83 OGA (0.43) OGAHRH3PIK3CAMTOR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11795165-B2 Tetrahydro-benzoazepine glycosidase inhibitors ASCENEURON SA (CH) 2023-10-24 US disclosed
US-11795165-B2 Tetrahydro-benzoazepine glycosidase inhibitors ASCENEURON SA (CH) 2023-10-24 US disclosed
WO-2020039028-A1 TETRAHYDRO-BENZOAZEPINE GLYCOSIDASE INHIBITORS ASCENEURON S. A. (CH) 2020-02-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11795165-B2 Tetrahydro-benzoazepine glycosidase inhibitors BACE1, BACE2, BCHE OGA 380/4885HRH3 650/4885PIK3CA 4245/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.