SCHEMBL21762016

SCHEMBL21762016

CSc1ccc2c(c1)CCN([C@@H](C)c1ccc3scnc3c1)CC2

nearest known ligand 0.49

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
OGA O60502 17/20 0.49
HTR2A P28223 1/20 0.35
HTR2C P28335 1/20 0.35
HTR2B P41595 1/20 0.35
PIK3CA P42336 2/20 0.35
MTOR P42345 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21762195 1.00 OGA (0.49) OGAHTR2AHTR2CHTR2BPIK3CA
SCHEMBL21762023 1.00 OGA (0.49) OGAHTR2AHTR2CHTR2BPIK3CA
SCHEMBL21762024 0.88 OGA (0.44) OGAHTR2AHTR2CHTR2BPIK3CA
SCHEMBL21762017 0.88 OGA (0.44) OGAHTR2AHTR2CHTR2BPIK3CA
SCHEMBL21762233 0.88 OGA (0.44) OGAHTR2AHTR2CHTR2BPIK3CA
SCHEMBL26622373 0.85 OGA (0.52) OGAPIK3CAMTOR
SCHEMBL21761983 0.85 OGA (0.55) OGAPIK3CAMTOR
SCHEMBL21761965 0.85 OGA (0.55) OGAPIK3CAMTOR
SCHEMBL21761961 0.85 OGA (0.55) OGAPIK3CAMTOR
SCHEMBL26608080 0.85 OGA (0.55) OGAPIK3CAMTOR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11795165-B2 Tetrahydro-benzoazepine glycosidase inhibitors ASCENEURON SA (CH) 2023-10-24 US disclosed
US-11795165-B2 Tetrahydro-benzoazepine glycosidase inhibitors ASCENEURON SA (CH) 2023-10-24 US disclosed
WO-2020039028-A1 TETRAHYDRO-BENZOAZEPINE GLYCOSIDASE INHIBITORS ASCENEURON S. A. (CH) 2020-02-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11795165-B2 Tetrahydro-benzoazepine glycosidase inhibitors BACE1, BACE2, BCHE OGA 380/4885HTR2A 754/4885HTR2C 1020/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.