Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21788107 | 0.95 | PDK2 (0.41) | PDK2KDM4EMAPTMEN1LMNA | |
| SCHEMBL21763101 | 0.92 | MEN1 (0.46) | PDK2KDM4EMAPTMEN1LMNA | |
| SCHEMBL21763099 | 0.92 | PDK2 (0.41) | PDK2KDM4EMAPTMEN1LMNA | |
| SCHEMBL21787756 | 0.90 | MEN1 (0.47) | PDK2KDM4EMAPTMEN1LMNA | |
| SCHEMBL21787836 | 0.88 | MEN1 (0.49) | PDK2KDM4EMAPTMEN1LMNA | |
| SCHEMBL21787896 | 0.85 | PDK2 (0.39) | PDK2KDM4EMAPTMEN1LMNA | |
| SCHEMBL21763102 | 0.85 | MEN1 (0.42) | PDK2KDM4EMAPTMEN1LMNA | |
| SCHEMBL21787897 | 0.85 | PDK2 (0.43) | PDK2MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL21416352 | 0.83 | PDK2 (0.43) | PDK2TDP1THRB | |
| SCHEMBL23544434 | 0.82 | PDK2 (0.44) | PDK2KDM4EMAPTMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3369719-B1 | SPIRO-TYPE COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME | LG CHEMICAL LTD (KR) | 2020-02-26 | — | — | EP | disclosed |