Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | CFTR | P13569 | 1/20 | 0.30 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21787836 | 0.97 | MEN1 (0.49) | MEN1KMT2ALMNAKDM4EMAPT | |
| SCHEMBL21787756 | 0.95 | MEN1 (0.47) | MEN1KMT2ALMNAKDM4EMAPT | |
| SCHEMBL21763102 | 0.93 | MEN1 (0.42) | MEN1KMT2ALMNAKDM4EMAPT | |
| SCHEMBL21763100 | 0.92 | PDK2 (0.42) | MEN1KMT2ALMNAKDM4EMAPT | |
| SCHEMBL21763412 | 0.88 | MEN1 (0.41) | MEN1KMT2ALMNAKDM4EMAPT | |
| SCHEMBL21787899 | 0.88 | PDE4D (0.40) | MEN1KMT2ALMNAKDM4EMAPT | |
| SCHEMBL21788107 | 0.87 | PDK2 (0.41) | MEN1KMT2ALMNAKDM4EMAPT | |
| SCHEMBL21763099 | 0.84 | PDK2 (0.41) | MEN1KMT2ALMNAKDM4EMAPT | |
| SCHEMBL15213745 | 0.84 | MEN1 (0.44) | MEN1KMT2ALMNAKDM4EMAPT | |
| SCHEMBL16996106 | 0.84 | MEN1 (0.44) | MEN1KMT2ALMNAKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3369719-B1 | SPIRO-TYPE COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME | LG CHEMICAL LTD (KR) | 2020-02-26 | — | — | EP | disclosed |